Evidence mapPaperPMID 32771313Full record

ArticleAcademic radiology2021

Deep Learning-based Quantification of Abdominal Subcutaneous and Visceral Fat Volume on CT Images.

Andrew T Grainger, Arun Krishnaraj, Michael H Quinones, Nicholas J Tustison, Samantha Epstein, Daniela Fuller, Aakash Jha, Kevin L Allman, Weibin Shi

Abstract read
In one paragraph

Article in Academic radiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Review
  2. Review
  3. Improved muscle and fat segmentation for body composition measures on quantitative CT.International journal of computer assisted radiology and surgery · 2025
    Article
  4. Article
  5. Article
  6. Article
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  8. Improved subcutaneous edema segmentation on abdominal CT using a generated adipose tissue density prior.International journal of computer assisted radiology and surgery · 2024
    Article
  9. Article
  10. Article
  11. Review
  12. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Andrew T GraingerDepartments of Biochemistry & Molecular Genetics, Richmond, Virginia.
Arun KrishnarajRadiology & Medical Imaging, School of Medicine, Virginia.
Michael H QuinonesRadiology & Medical Imaging, School of Medicine, Virginia.
Nicholas J TustisonRadiology & Medical Imaging, School of Medicine, Virginia.
Samantha EpsteinRadiology & Medical Imaging, School of Medicine, Virginia.
Daniela FullerSchool of Engineering and Applied Science, University of Virginia, 480 Ray C. Hunt Drive, Charlottesville, VA 22908.
Aakash JhaSchool of Engineering and Applied Science, University of Virginia, 480 Ray C. Hunt Drive, Charlottesville, VA 22908.
Kevin L AllmanSchool of Engineering and Applied Science, University of Virginia, 480 Ray C. Hunt Drive, Charlottesville, VA 22908.
Weibin ShiDepartments of Biochemistry & Molecular Genetics, Richmond, Virginia; Radiology & Medical Imaging, School of Medicine, Virginia. Electronic address: ws4v@virginia.edu.

Funding

Genetic connections between type 2 diabetes and atherosclerosisR01DK116768 · NIDDK · UNIVERSITY OF VIRGINIA · PI WEIBIN SHI · 2022 to 2022
$399k
NIDDK NIH HHS R01 DK116768
6 · The paper itself

Abstract

RATIONALE AND

objectivesDevelop a deep learning-based algorithm using the U-Net architecture to measure abdominal fat on computed tomography (CT) images. MATERIALS AND

methodsSequential CT images spanning the abdominal region of seven subjects were manually segmented to calculate subcutaneous fat (SAT) and visceral fat (VAT). The resulting segmentation maps of SAT and VAT were augmented using a template-based data augmentation approach to create a large dataset for neural network training. Neural network performance was evaluated on both sequential CT slices from three subjects and randomly selected CT images from the upper, central, and lower abdominal regions of 100 subjects.

resultsBoth subcutaneous and abdominal cavity segmentation images created by the two methods were highly comparable with an overall Dice similarity coefficient of 0.94. Pearson's correlation coefficients between the subcutaneous and visceral fat volumes quantified using the two methods were 0.99 and 0.99 and the overall percent residual squared error were 5.5% and 8.5%. Manual segmentation of SAT and VAT on the 555 CT slices used for testing took approximately 46 hours while automated segmentation took approximately 1 minute.

conclusionOur data demonstrates that deep learning methods utilizing a template-based data augmentation strategy can be employed to accurately and rapidly quantify total abdominal SAT and VAT with a small number of training images.

Indexed as

Deep LearningIntra-Abdominal FatAbdominal FatHumansSubcutaneous FatTomography, X-Ray Computedartificial intelligenceDeep learningobesityvisceral fat

Identifiers

PMID32771313
PMCPMC7862413

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.