Evidence map›Paper›PMID 32783016›Full record

ArticleJournal of the Endocrine Society2020

A Rare Case of Recurrent Pituitary Collision Tumors.

Almoutaz Shakally, Naoyuki Tahara, Brent Clark, Ramachandra Tummala, Emiro Caicedo-Granados, Yasuhiko Kawakami, Takako Araki

Open access · goldAbstract readCase Reports
In one paragraph

Article in Journal of the Endocrine Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact, top 88% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Almoutaz ShakallyDivision of Diabetes, Endocrinology and Metabolism, Department of Medicine, University of Minnesota, Minneapolis, Minnesota.
Naoyuki TaharaDepartment of Genetics, Cell Biology and Development, University of Minnesota, Minneapolis, Minnesota.
Brent ClarkDepartment of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, Minnesota.
Ramachandra TummalaDepartment of Neurosurgery, University of Minnesota, Minneapolis, Minnesota.ORCID 0000-0002-1905-2906
Emiro Caicedo-GranadosDepartment of Otolaryngology, Head and Neck Surgery, University of Minnesota, Minneapolis, Minnesota.
Yasuhiko KawakamiDepartment of Genetics, Cell Biology and Development, University of Minnesota, Minneapolis, Minnesota.ORCID 0000-0002-0043-9705
Takako ArakiDivision of Diabetes, Endocrinology and Metabolism, Department of Medicine, University of Minnesota, Minneapolis, Minnesota.ORCID 0000-0002-4451-1668
University of Minnesota · US

Funding

Genetic Regulation of Progenitor Cells in Appendicular Skeletal DevelopmentR01AR064195 · NIAMS · UNIVERSITY OF MINNESOTA · PI KAWAKAMI, YASUHIKO · 2013 to 2022
$3.3M
NIAMS NIH HHS R01 AR064195
6 · The paper itself

Abstract

Pituitary collision tumors are sporadically reported and rare. We present a case of pituitary collision tumors with nonfunctioning pituitary adenoma (NFPA) and craniopharyngioma. In order to look for any common activated pathway, we examined WNT/β-CATENIN signaling activation, known to be involved in tumorigenesis in both craniopharyngioma and NFPA. We found nuclear accumulation of β-CATENIN protein and expression of LEF1 protein, markers of active β-CATENIN signaling in the craniopharyngioma but not in the pituitary adenomas. In our case, the NFPA is invasive macroadenoma, which is a frequently identified type of pituitary adenoma in collision tumor cases. Recurrence of this tumor was first observed after 8 years of follow-up. Based on this case, we suggest that pituitary collision tumors require long-term follow-up.

Identifiers

PMID32783016
PMCPMC7412853
OpenAlexW3039494254

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.