ArticleThe international journal of cardiovascular imaging2021
Distribution of myocardial work in arterial hypertension: insights from non-invasive left ventricular pressure-strain relations.
Article in The international journal of cardiovascular imaging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.
- Assessing Myocardial Strain and Myocardial Work as a Marker for Hypertensive Heart Disease: A Meta-Analysis.Reviews in cardiovascular medicine · 2023Pooled it
- Ventricular preexcitation-induced subclinical LV dysfunction: Insights from pressure-strain loop imaging.American heart journal plus : cardiology research and practice · 2026Article
- Assessment of ventricular-arterial coupling in early stage middle-aged hypertensives.Journal of human hypertension · 2025Observational
- Cardiac adaptations in young triathletes: a 9-month longitudinal study during the peak height velocity period.European journal of applied physiology · 2025Article
- Assessment of Ventricular-Arterial Coupling in Early Stage Middle-Aged Hypertensives.Research square · 2025Article
- Three-dimensional structure of entire hydrated murine hearts at histological resolution.Scientific reports · 2025Article
- Study on the ultrasonic myocardial mechanics of left atrioventricular coupling in IBSH patients.Frontiers in cardiovascular medicine · 2025Article
- Evaluation of global and regional myocardial work by echocardiography in patients with Fabry disease.Orphanet journal of rare diseases · 2024Article
- The clinical value of noninvasive left ventricular myocardial work in the diagnosis of myocardial ischemia in coronary heart disease: a comparative study with coronary flow reserve fraction.The international journal of cardiovascular imaging · 2024Article
- Usability of myocardial work parameters to demonstrate subclinical myocardial involvement in normotensive individuals with exaggerated hypertensive response in treadmill exercise testing.Journal of clinical hypertension (Greenwich, Conn.) · 2024Article
- Echocardiographic Myocardial Work: A Novel Method to Assess Left Ventricular Function in Patients with Coronary Artery Disease and Diabetes Mellitus.Medicina (Kaunas, Lithuania) · 2024Review
- Evaluation of subclinical left ventricular systolic dysfunction in obese patients by global myocardial work.Diabetology & metabolic syndrome · 2023Article
- Segmental and global myocardial work in hypertensive patients with different left ventricular ejection fraction: what's the role of the apex played?The international journal of cardiovascular imaging · 2023Article
- Segmental and global myocardial work in hypertensive patients with different left ventricular geometry.Cardiovascular ultrasound · 2023Article
- Left Ventricle Segmental Longitudinal Strain and Regional Myocardial Work Index Could Help Determine Mitral Valve Prolapse Patients with Increased Risk of Ventricular Arrhythmias.Journal of cardiovascular development and disease · 2023Article
- Assessment of left ventricular myocardial work done by noninvasive pressure-strain loop technique in patients with essential hypertension.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2022Article
- Prognostic value of myocardial work and global longitudinal strain in patients with heart failure and functional mitral regurgitation.The international journal of cardiovascular imaging · 2022Article
- Impact of Brachial-Ankle Pulse Wave Velocity on Myocardial Work by Non-invasive Left Ventricular Pressure-Strain in Non-hypertensive and Hypertensive Patients With Preserved Left Ventricular Ejection Fraction.Frontiers in cardiovascular medicine · 2022Article
- Non-invasive global myocardial work index as a new surrogate of ventricular-arterial coupling in hypertensive patients with preserved left ventricular ejection fraction.Frontiers in cardiovascular medicine · 2022Article
- Advanced imaging tools for evaluating cardiac morphological and functional impairment in hypertensive disease.Journal of hypertension · 2022Review
Corrections and comments
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Authors and funding
13 authors at 5 institutions in 3 countries.
Funding
Abstract
A index of non-invasive myocardial work (MWI) can account for pressure during the assessment of cardiac function, potentially separating the influence of loading conditions from the influence of the underlying tissue remodelling. The aim is to assess LV function accounted for loading and explore hypertensive MWI distribution by comparing healthy individuals to hypertensive patients without and with localized basal septal hypertrophy (BSH). An echocardiogram was performed in 170 hypertensive patients and 20 healthy individuals. BSH was defined by a basal-to-mid septal wall thickness ratio ≥ 1.4. LV speckle-tracking was performed, and the MWI calculated globally and regionally for the apical, mid and basal regions. An apex-to-base gradient, seen in regional strain values, was preserved in the distribution of myocardial work, with the apical region compensating for the impairment of the basal segments. This functional redistribution was further pronounced in patients with localized BSH. In these patients, segmental MWI analysis revealed underlying impairment of regional work unrelated to acute loading conditions. Non-invasive MWI analysis offers the possibility to compare LV function regardless of blood pressure at the time of observation. Changes in MWI distribution can be seen in hypertension unrelated to the load-dependency of strain. Accentuated functional changes affirm the role of BSH as an echocardiographic marker in hypertension.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.