Evidence map›Paper›PMID 32789576›Full record

ReviewMolecular biology reports2020

Advances of exosome isolation techniques in lung cancer.

Elham O Mahgoub, Ehsan Razmara, Amirreza Bitaraf, Fahimeh-Sadat Norouzi, Maryam Montazeri, Roudabeh Behzadi-Andouhjerdi, Mojtaba Falahati, Ke Cheng, Yousif Haik, Anwarul Hasan and 1 more

Abstract readReview
PubMed Publisher
In one paragraph

Review in Molecular biology reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Engineering of Cell Derived-Nanovesicle as an Alternative to Exosome Therapy.Tissue engineering and regenerative medicine · 2024
    Review
  11. Review
  12. Review
  13. Review
  14. Article
  15. Review
  16. Article
  17. Article
  18. SMAD4 contributes to chondrocyte and osteocyte development.Journal of cellular and molecular medicine · 2022
    Review
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 3 countries.

Elham O MahgoubDepartment of Science and Engineering, Hamad Bin Khalifa University, Qatar Foundation, Education City, Doha, Qatar.
Ehsan RazmaraDepartment of Medical Genetics, School of Medical Sciences, Tarbiat Modares University, Tehran, Iran.
Amirreza BitarafDepartment of Molecular Genetics, Faculty of Biological Sciences, Tarbiat Modares University, P.O. Box: 14115-154, Tehran, Iran.
Fahimeh-Sadat NorouziDepartment of Molecular Genetics, Faculty of Biological Sciences, Tarbiat Modares University, P.O. Box: 14115-154, Tehran, Iran.
Maryam MontazeriDepartment of Medical Biotechnology, Faculty of Advanced Science and Technology, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran.
Roudabeh Behzadi-AndouhjerdiDepartment of Biology, Central Branch, Islamic Azad University, Tehran, Iran.
Mojtaba FalahatiDepartment of Nanotechnology, Faculty of Advanced Science and Technology, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran.
Ke ChengJoint Department of Biomedical Engineering, The University of North Carolina at Chapel Hill, North Carolina State University, NC, Raleigh, USA.
Yousif HaikDepartment of Science and Engineering, Hamad Bin Khalifa University, Qatar Foundation, Education City, Doha, Qatar.
Anwarul HasanDepartment of Mechanical and Industrial Engineering, College of Engineering, Qatar University, 2713, Doha, Qatar. ahasan@qu.edu.qa.
Sadegh BabashahDepartment of Molecular Genetics, Faculty of Biological Sciences, Tarbiat Modares University, P.O. Box: 14115-154, Tehran, Iran. sadegh.babashah@gmail.com.ORCID http://orcid.org/0000-0001-7066-0918
Tarbiat Modares University · IRHamad bin Khalifa University · QAIslamic Azad University Medical Branch of Tehran · IRIslamic Azad University Central Tehran Branch · IRQatar University · QAUniversity of North Carolina at Chapel Hill · US

Funding

Qatar National Research Fund NPRP10-0120-170211
6 · The paper itself

Abstract

Lung cancer (LC) is among the leading causes of death all over the world and it is often diagnosed at advanced or metastatic stages. Exosomes, derived from circulating vesicles that are released from the multivesicular body, can be utilized for diagnosis and also the prognosis of LC at early stages. Exosomal proteins, RNAs, and DNAs can help to better discern the prognostic and diagnostic features of LC. To our knowledge, there are various reviews on LC and the contribution of exosomes, but none of them are about the exome techniques and also their efficiency in LC. To fill this gap, in this review, we summarize the recent investigations regarding isolation and also the characterization of exosomes of LC cells. Furthermore, we discuss the noncoding RNAs as biomarkers and their applications in the diagnosis and prognosis of LC. Finally, we compare the efficacy of exosome isolation methods to better fi + 6 + guring out feasible techniques.

Indexed as

Biomarkers, TumorCell-Free Nucleic AcidsCirculating Tumor DNAExosomesHumansLung NeoplasmsBiomarkers, TumorCell-Free Nucleic AcidsCirculating Tumor DNAExosomeExtracellular vesiclesLung cancerMicroRNAsMulti-vesicular bodies

Identifiers

PMID32789576
OpenAlexW3048837586

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.