Evidence map›Paper›PMID 32789749›Full record

ReviewCurrent heart failure reports2020

New Insights in RBM20 Cardiomyopathy.

D Lennermann, J Backs, M M G van den Hoogenhof

Open access · hybridAbstract readReview
In one paragraph

Review in Current heart failure reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 1 pooled it
5.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 1 synthesis or guideline pooled it, 61 citations in OpenAlex.

  1. Pooled it
  2. Novel Truncating Variant c.1222DupC inCirculation. Genomic and precision medicine · 2026
    Article
  3. Review
  4. Article
  5. Early Onset Heart Failure due toClinical case reports · 2026
    Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. RNA-Binding Proteins in Cardiomyopathies.Journal of cardiovascular development and disease · 2024
    Review
  14. RNA binding proteins in cardiovascular development and disease.Current topics in developmental biology · 2024
    Article
  15. Review
  16. [Research progress on the expression of theZhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2023
    Review
  17. Article
  18. Review
  19. Precise genomic editing of pathogenic mutations inScience translational medicine · 2022
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

D LennermannInstitute of Experimental Cardiology, Heidelberg University Hospital, Heidelberg, Germany.
J BacksInstitute of Experimental Cardiology, Heidelberg University Hospital, Heidelberg, Germany.
M M G van den HoogenhofInstitute of Experimental Cardiology, Heidelberg University Hospital, Heidelberg, Germany. maarten.vandenhoogenhof@med.uni-heidelberg.de.
German Centre for Cardiovascular Research · DEHeidelberg University · DEUniversity Hospital Heidelberg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewThis review aims to give an update on recent findings related to the cardiac splicing factor RNA-binding motif protein 20 (RBM20) and RBM20 cardiomyopathy, a form of dilated cardiomyopathy caused by mutations in RBM20. RECENT

findingsWhile most research on RBM20 splicing targets has focused on titin (TTN), multiple studies over the last years have shown that other splicing targets of RBM20 including Ca

Indexed as

MutationCardiomyopathy, DilatedDNADNA Mutational AnalysisHumansMyocytes, CardiacRNA-Binding ProteinsDNAribonucleic acid binding motif protein 20, humanRNA-Binding ProteinsCalcium handlingCaMKIIδDilated cardiomyopathyGender differencesRBM20Titin

Identifiers

PMID32789749
PMCPMC7495990
OpenAlexW3049272392

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.