Evidence map›Paper›PMID 32800649›Full record

SynthesisPancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]2020

Coexistence of alcohol-related pancreatitis and alcohol-related liver disease: A systematic review and meta-analysis.

Ajay Singhvi, Rebecca Abromitis, Andrew D Althouse, Ramon Bataller, Gavin E Arteel, Dhiraj Yadav

Erratum issuedOpen access · greenAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.], 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Case of severe alcoholic hepatitis following acute pancreatitis.Clinical journal of gastroenterology · 2024
    Article
  5. Article
  6. Article
  7. Observational
  8. Article
  9. Article
  10. Extrahepatic Manifestations in Alcoholic Liver Disease.Journal of clinical and experimental hepatology
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Ajay SinghviDivision of Gastroenterology, Hepatology & Nutrition, University of Pittsburgh Medical Center, Pittsburgh, PA, United States.
Rebecca AbromitisHealth Sciences Library System, University of Pittsburgh, Pittsburgh, PA, United States.
Andrew D AlthouseDivision of General Internal Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA, United States.
Ramon BatallerDivision of Gastroenterology, Hepatology & Nutrition, University of Pittsburgh Medical Center, Pittsburgh, PA, United States.
Gavin E ArteelDivision of Gastroenterology, Hepatology & Nutrition, University of Pittsburgh Medical Center, Pittsburgh, PA, United States.
Dhiraj YadavDivision of Gastroenterology, Hepatology & Nutrition, University of Pittsburgh Medical Center, Pittsburgh, PA, United States. Electronic address: yadavd@upmc.edu.
University of Pittsburgh Medical Center · USUniversity of Pittsburgh · USUPMC Health System · US

Funding

The Role of Nutrition in the Development/Progression of Alcohol-Induced Organ InjuryP50AA024337 · NIAAA · UNIVERSITY OF LOUISVILLE · PI Xiang Zhang · 2016 to 2026
$17.9M
Pittsburgh Liver Research CenterP30DK120531 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Satdarshan Singh Monga · 2019 to 2026
$10.9M
UPMC Clinical Center for the Study of Chronic Pancreatitis and DiabetesU01DK108306 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Frederico G. S. Toledo, Dhiraj Yadav · 2015 to 2026
$6.4M
Patient-centered and efficacious advance care planning in cancer: the PEACe comparative effectiveness trialR01CA235730 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI SCHENKER, YAEL · 2019 to 2024
$3.1M
Biomarkers of Alcoholic HepatitisR01AA028436 · NIAAA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI ARTEEL, GAVIN E, BENOS, PANAGIOTIS V · 2020 to 2024
$3.0M
Research Supplements to Promote Diversity in Health-Related ResearchU01GM132133 · NIGMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MORONE, NATALIA E., MURRELL, AUDREY JEANETTE · 2019 to 2023
$2.8M
Role of ECM and inflammatory remodeling in alcohol-induced liver and lung damage-diversity supplementR01AA021978 · NIAAA · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI ARTEEL, GAVIN E · 2014 to 2018
$1.8M
Regulation of MEKK3 by Oxidative StressR01AG019710 · NIA · UNIVERSITY OF ARIZONA · PI VAILLANCOURT, RICHARD R · 2001 to 2005
$1.2M
A Mobile Relational Agent to Enhance Atrial Fibrillation Self-careR61HL144669 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MAGNANI, JARED W. · 2019 to 2019
$766k
Cardiac Resynchronization in the Elderly: Piloting Pacemaker vs. Defibrillator TherapyR34HL132031 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI SABA, SAMIR FAWZI · 2017 to 2018
$700k
Testing the Effectiveness of the Customized Career Development Platform (CCDP): A Cluster Randomized TrialR21TR003094 · NCATS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI PATINO SUTTON, CECILIA MARIA, RUBIO, DORIS M · 2020 to 2021
$432k
NCATS NIH HHS R21 TR003094NCI NIH HHS R01 CA235730NHLBI NIH HHS R34 HL132031NHLBI NIH HHS R61 HL144669NIAAA NIH HHS P50 AA024337NIAAA NIH HHS R01 AA021978NIAAA NIH HHS R01 AA028436NIA NIH HHS R01 AG019710NIDDK NIH HHS P30 DK120531NIDDK NIH HHS U01 DK108306NIGMS NIH HHS U01 GM132133
6 · The paper itself

Abstract

backgroundAvailable estimates of coexistent alcohol-related pancreatitis (ALP) and alcohol-related liver disease (ALD) vary widely, and factors that determine coexistent disease are largely unknown. We performed a systematic review of published literature with the primary aim to generate robust estimates for coexistent alcohol-related chronic pancreatitis (ACP) and alcohol-related cirrhosis (ALC).

methodsWe searched PubMed, EMBASE, and Web of Science databases from inception until February 2018. Studies included were those in English-language, sample size ≥25 and allowed calculation of the coexistent disease. Pooled estimates were calculated using a random-effects model approach.

resultsTwenty-nine (including 5 autopsy studies) of 2000 eligible studies met inclusion criteria. Only 6.9% included patients were female. Fifteen studies enabled calculation of ACP in ALC, and 11 for ALC in ACP. Pooled prevalence of ACP in ALC was 16.2% (95% CI 10.4-24.5) overall, and 15.5% (95% CI 8.0-27.7) when data were limited to clinical studies. Corresponding prevalence for ALC in ACP was 21.5% (95% CI 12.0-35.6) and 16.9% (95% CI 11.5-24.3), respectively. There was significant heterogeneity among studies (I

conclusionA sizeable fraction of patients with ACP or ALC have coexistent disease. Future studies should define the prevalence of coexistent disease in women and minority populations, and the consequences of coexistent disease on clinical presentation and short- and long-term outcomes.

Indexed as

FemaleHepatitis, AlcoholicHumansLiver Cirrhosis, AlcoholicMalePancreatitis, Alcoholic

Identifiers

PMID32800649
PMCPMC7970449
OpenAlexW3046203250

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.