Evidence map›Paper›PMID 32801434›Full record

ArticleMedical archives (Sarajevo, Bosnia and Herzegovina)2020

Assessment of Retinal Microangiopathy in Chronic Kidney Disease Patients.

Aida Kasumovic, Ines Matoc, Damir Rebic, Nesina Avdagic, Tarik Halimic

Open access · greenAbstract read
In one paragraph

Article in Medical archives (Sarajevo, Bosnia and Herzegovina), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.2field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Aida KasumovicEye Polyclinic "Dr. Sefić", Sarajevo, Bosnia and Herzegovina.
Ines MatocEye Polyclinic "Dr. Sefić", Sarajevo, Bosnia and Herzegovina.
Damir RebicUniversity Clinical Center Sarajevo, Nephrology Clinic, Sarajevo, Bosnia and Herzegovina.
Nesina AvdagicDepartment of Human Physiology, Faculty of Medicine, University of Sarajevo, Bosnia and Herzegovina.
Tarik HalimicEye Polyclinic "Dr. Sefić", Sarajevo, Bosnia and Herzegovina.
University of Sarajevo · BA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionOptical coherence tomography angiography (OCT-A) is a useful diagnostic tool for assessing eyes' health in patients with chronic diseases, such as diabetes, hypertension, Parkinson's disease and chronic kidney disease (CKD).

aimTo detect changes in macular structure and retinal vascular meshwork in the macular area and peripapillary in patients with chronic kidney disease (CKD).

methodsThis cross-sectional study included 80 eyes of patients with CKD in stages 2, 3 or 4, who were followed-up in the Nephrology Clinic of University Clinical Center Sarajevo. All patients were categorized according to the stage of CKD. All patients were scanned by a high-speed 840-nm-wavelength spectral-domain optical coherence tomography instrument (RTVue XR Avanti; Optovue, Inc, Fremont, California, USA). Blood flow was detected using a split-spectrum amplitude-decorrelation angiography algorithm. A fully automated microstructural analysis of the foveal avascular zone (FAZ), FAZ perimeter, foveal vessel density in a 300-μm area around the FAZ (FD), nonflow area, flow index in superficial and deep vascular plexus, choriocapillary flow, vascular density, radial peripapillary capillary density was performed.

resultsWhen comparing patients with CKD stage 2 and stage 3 there were no statistically significant changes in microvascular parameters on OCT angiography, as well as when comparing patients with CKD stage 3 and stage 4. But in the comparison between patients with less developed CKD (stage 2) and terminal CKD (stage 4) there was a significant difference between some microvascular parameters such as FAZ area, FAZ perimeter, choriocapillary flow.

conclusionMany studies demonstrated that evaluation of the microvascular changes in different retinal layers using SS-OCTA may be considered as a key to assessing the systemic perfusion status. Evaluation of retinal microvasculature may ease the management and approach of patients with CKD, having in mind that the retinal and the kidney vascular network are, concerning structure, development and the function, very similar.

Indexed as

AgedAged, 80 and overAngiographyCross-Sectional StudiesFemaleFovea CentralisHumansMaleMicrocirculationMicrovesselsMiddle AgedRegional Blood FlowRenal Insufficiency, ChronicRetinal DiseasesRetinal VesselsTomography, Optical Coherencechronic kidney diseasemicroangiopathyoptical coherence tomography angiographyretinal angiopathy

Identifiers

PMID32801434
PMCPMC7406003
OpenAlexW3036489675

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.