Evidence map›Paper›PMID 32801815›Full record

ArticleDiabetes, metabolic syndrome and obesity : targets and therapy2020

Obesity of

David R Powell, Deon D Doree, Christopher M DaCosta, Kenneth A Platt, Gwenn M Hansen, Isaac van Sligtenhorst, Zhi-Ming Ding, Jean-Pierre Revelli, Robert Brommage

Open access · goldAbstract read
In one paragraph

Article in Diabetes, metabolic syndrome and obesity : targets and therapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Mice LackingDiabetes, metabolic syndrome and obesity : targets and therapy · 2022
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

David R PowellLexicon Pharmaceuticals Inc, The Woodlands, TX, 77381, USA.ORCID 0000-0001-8072-388X
Deon D DoreeLexicon Pharmaceuticals Inc, The Woodlands, TX, 77381, USA.
Christopher M DaCostaLexicon Pharmaceuticals Inc, The Woodlands, TX, 77381, USA.
Kenneth A PlattLexicon Pharmaceuticals Inc, The Woodlands, TX, 77381, USA.
Gwenn M HansenLexicon Pharmaceuticals Inc, The Woodlands, TX, 77381, USA.ORCID 0000-0003-2504-5849
Isaac van SligtenhorstLexicon Pharmaceuticals Inc, The Woodlands, TX, 77381, USA.ORCID 0000-0002-4789-3104
Zhi-Ming DingLexicon Pharmaceuticals Inc, The Woodlands, TX, 77381, USA.
Jean-Pierre RevelliLexicon Pharmaceuticals Inc, The Woodlands, TX, 77381, USA.
Robert BrommageLexicon Pharmaceuticals Inc, The Woodlands, TX, 77381, USA.ORCID 0000-0002-9947-3822
Lexicon Pharmaceuticals (United States) · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeIn humans, single nucleotide polymorphisms (SNPs) near the adjacent protein kinase D1 (

methodsThe

resultsBody fat was increased in multiple cohorts of

conclusionSignificant obesity and glucose intolerance were observed in

Indexed as

gene trapglucose tolerancehomologous recombinationPrkd1PRKD1SNP

Identifiers

PMID32801815
PMCPMC7394505
OpenAlexW3044931952

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.