Evidence map›Paper›PMID 32802139›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2020

Traditional Chinese Medicine Da-Cheng-Qi-Tang Ameliorates Impaired Gastrointestinal Motility and Intestinal Inflammatory Response in a Mouse Model of Postoperative Ileus.

Chunqiu Chen, Min Li, Xiaohong Liu, Jianwei Fan, Hong Zhang, Sisi Lin, Lu Yin, Jakub Fichna, Yongyu Li

Open access · hybridAbstract read
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Chunqiu ChenDepartment of General Surgery, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai 200072, China.
Min LiDepartment of Physiology, Zunyi Medical College, Zunyi 563000, China.
Xiaohong LiuDepartment of Physiology, Zunyi Medical College, Zunyi 563000, China.
Jianwei FanMedical Experiment Center, Shaanxi University of Chinese Medicine, Xianyang, Shaanxi 712046, China.
Hong ZhangMedical Experiment Center, Shaanxi University of Chinese Medicine, Xianyang, Shaanxi 712046, China.
Sisi LinInstitute of Digestive Disease, Tongji University School of Medicine, Shanghai 200092, China.
Lu YinDepartment of General Surgery, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai 200072, China.
Jakub FichnaDepartment of Biochemistry, Faculty of Medicine, Medical University of Lodz, Lodz, Poland.
Yongyu LiInstitute of Digestive Disease, Tongji University School of Medicine, Shanghai 200092, China.ORCID https://orcid.org/0000-0001-8704-349X
Tongji University · CNShaanxi University of Chinese Medicine · CNZunyi Medical University · CNMedical University of Lodz · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study was to explore the therapeutic effect and mechanism of the traditional Chinese medicine with the formula Da-Cheng-Qi-Tang (T-DCQT) and a modified Da-Cheng-Qi-Tang (M-DCQT) in a postoperative ileus (POI) mouse model. POI was induced via small bowel manipulation, and T-DCQT or M-DCQT was given by enema. The intestinal motility was measured with a charcoal mixture gavage. The intestinal tissues were collected for further studies by histopathological, qPCR, immunohistochemical staining, and Western blotting. Levels of inflammatory cytokines in blood were determined using a high-throughput liquid chip. We found that gastrointestinal dysfunction was alleviated after administration of either a T-DCQT or M-DCQT enema. Increased expression of NF-

Identifiers

PMID32802139
PMCPMC7415087
OpenAlexW3046349871

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.