Evidence map›Paper›PMID 32802813›Full record

ArticleAnnals of surgical treatment and research2020

The prognoses and postoperative outcomes of patients with both colorectal cancer and liver cirrhosis based on a nationwide cohort in Korea.

Nari Shin, Eon Chul Han, Sungho Won, Seung-Bum Ryoo, Eun Kyung Choe, Byung Kwan Park, Kyu Joo Park

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Annals of surgical treatment and research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Nari ShinDepartment of Public Health Sciences and Institute of Health and Environment, Seoul National University, Seoul, Korea.ORCID https://orcid.org/0000-0001-8447-5887
Eon Chul HanDepartment of Surgery, Dongnam Institute of Radiological and Medical Sciences, Busan, Korea.ORCID https://orcid.org/0000-0001-5987-3752
Sungho WonDepartment of Public Health Sciences and Institute of Health and Environment, Seoul National University, Seoul, Korea.ORCID https://orcid.org/0000-0001-5751-5089
Seung-Bum RyooDepartment of Surgery, Seoul National University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0001-6407-0444
Eun Kyung ChoeDepartment of Surgery, Seoul National University Hospital Healthcare System Gangnam Center, Seoul, Korea.ORCID https://orcid.org/0000-0002-7222-1772
Byung Kwan ParkDepartment of Surgery, Chung-Ang University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-2283-8483
Kyu Joo ParkDepartment of Surgery, Seoul National University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-9134-7426
Seoul National University · KRChung-Ang University · KRDongnam Institute of Radiological & Medical Sciences · KRKorea National Institute of Health · KRSeoul National University Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe management of patients with colorectal cancer (CRC) who have liver cirrhosis (LC) requires a thorough understanding of both diseases; however, the prognoses and postoperative outcomes of such patients remain understudied. We investigated the effect of LC on surgical and oncologic outcomes in patients with CRC, and identified prognostic factors.

methodsWe analyzed 453 patients with CRC and LC (CRC-LC group), 906 with CRC only (CRC group), 906 with LC only (LC group), and 1,812 healthy subjects using health insurance claim data (2008-2013).

resultsThe CRC-LC group had a higher frequency of intensive care unit admission than the CRC group; there were no differences between the 2 groups in terms of early and late postoperative small bowel obstruction and incisional hernia. However, the 30-day, 60-day, and 90-day mortality rates were all significantly higher in the CRC-LC group. The higher Charlson comorbidity index (hazard ratio [HR], 1.127) and the lower socioeconomic status (HR, 0.985) were significant worse predictors of 5-year survival. Patients with underlying LC had a significantly higher HR in both the advanced CRC (HR, 1.858) and nonadvanced CRC (HR, 1.799) subgroups. However, the nonadvanced CRC subgroup showed a lower HR than the LC group (HR, 0.730).

conclusionPatients with CRC who had underlying LC had a lower survival rate than did those without LC, although the incidence rates of postoperative complications were not significantly different. The presence of LC was associated with a significantly lower survival rate regardless of CRC presence.

Indexed as

Colorectal neoplasmsComplicationLiver cirrhosisOncological results

Identifiers

PMID32802813
PMCPMC7406393
OpenAlexW3047454187

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.