Evidence map›Paper›PMID 32803873›Full record

ReviewEMBO reports2020

So close, no matter how far: multiple paths connecting transcription to mRNA translation in eukaryotes.

Boris Slobodin, Rivka Dikstein

Open access · bronzeAbstract readReview
In one paragraph

Review in EMBO reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 36 citations in OpenAlex.

  1. eIF5A coordinates the transcription and translation of its target genes.Cellular and molecular life sciences : CMLS · 2026
    Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Review
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  11. Article
  12. Review
  13. Epigenetics · 2022
    Article
  14. Article
  15. The recipe for cytonuclear interaction begins with a superabundance of plastid and mitochondrial mRNAs.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Boris SlobodinDepartment of Biomolecular Sciences, The Weizmann Institute of Science, Rehovot, Israel.ORCID 0000-0002-6324-2715
Rivka DiksteinDepartment of Biomolecular Sciences, The Weizmann Institute of Science, Rehovot, Israel.ORCID 0000-0002-6251-4723
Weizmann Institute of Science · IL

Funding

Israel Cancer Association (ICA) 20180113Israel Science Foundation (ISF) 843/17
6 · The paper itself

Abstract

Transcription of DNA into mRNA and translation of mRNA into proteins are two major processes underlying gene expression. Due to the distinct molecular mechanisms, timings, and locales of action, these processes are mainly considered to be independent. During the last two decades, however, multiple factors and elements were shown to coordinate transcription and translation, suggesting an intricate level of synchronization. This review discusses the molecular mechanisms that impact both processes in eukaryotic cells of different origins. The emerging global picture suggests evolutionarily conserved regulation and coordination between transcription and mRNA translation, indicating the importance of this phenomenon for the fine-tuning of gene expression and the adjustment to constantly changing conditions.

Indexed as

EukaryotaProtein BiosynthesisEukaryotic CellsRNA, MessengerRNA, Messengergene expressionIRESm6AmRNA translationtranscription

Identifiers

PMID32803873
PMCPMC7507372
OpenAlexW3049341910

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.