Evidence map›Paper›PMID 32806937›Full record

ReviewCancer control : journal of the Moffitt Cancer Center

Power and Promise of Next-Generation Sequencing in Liquid Biopsies and Cancer Control.

Ting-Miao Wu, Ji-Bin Liu, Yu Liu, Yi Shi, Wen Li, Gao-Ren Wang, Yu-Shui Ma, Da Fu

Abstract readReview
In one paragraph

Review in Cancer control : journal of the Moffitt Cancer Center. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Building Disease Models for Endometriosis: iPSCs as Game-Changers.International journal of molecular sciences · 2026
    Review
  2. Review
  3. Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. Liquid Biopsy in the Clinical Management of Cancers.International journal of molecular sciences · 2024
    Review
  9. Article
  10. Liquid biopsies: the future of cancer early detection.Journal of translational medicine · 2023
    Review
  11. Review
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ting-Miao WuDepartment of Radiology, 12485The Fourth Affiliated Hospital of Anhui Medical University, Hefei, China.
Ji-Bin LiuCancer Institute, 377323Nantong Tumor Hospital, Nantong, China.
Yu LiuNational Engineering Laboratory for Rice and By-product Deep Processing, College of Food Science and Engineering, 12571Central South University of Forestry and Technology, Chaha, China.
Yi ShiNational Engineering Laboratory for Rice and By-product Deep Processing, College of Food Science and Engineering, 12571Central South University of Forestry and Technology, Chaha, China.
Wen LiNational Engineering Laboratory for Rice and By-product Deep Processing, College of Food Science and Engineering, 12571Central South University of Forestry and Technology, Chaha, China.
Gao-Ren WangCancer Institute, 377323Nantong Tumor Hospital, Nantong, China.
Yu-Shui MaCancer Institute, 377323Nantong Tumor Hospital, Nantong, China.
Da FuDepartment of Radiology, 12485The Fourth Affiliated Hospital of Anhui Medical University, Hefei, China.ORCID https://orcid.org/0000-0002-0878-2575

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Traditional methods of cancer treatment are usually based on the morphological and histological diagnosis of tumors, and they are not optimized according to the specific situation. Precision medicine adjusts the existing treatment regimen based on the patient's genomic information to make it most suitable for patients. Detection of genetic mutations in tumors is the basis of precise cancer medicine. Through the analysis of genetic mutations in patients with cancer, we can tailor the treatment plan for each patient with cancer to maximize the curative effect, minimize damage to healthy tissues, and optimize resources. In recent years, next-generation sequencing technology has developed rapidly and has become the core technology of precise targeted therapy and immunotherapy for cancer. From early cancer screening to treatment guidance for patients with advanced cancer, liquid biopsy is increasingly used in cancer management. This is as a result of the development of better noninvasive, repeatable, sensitive, and accurate tools used in early screening, diagnosis, evaluation, and monitoring of patients. Cell-free DNA, which is a new noninvasive molecular pathological detection method, often carries tumor-specific gene changes. It plays an important role in optimizing treatment and evaluating the efficacy of different treatment options in clinical trials, and it has broad clinical applications.

Indexed as

Cell-Free Nucleic AcidsHigh-Throughput Nucleotide SequencingHumansImmunotherapyImmunotherapy, AdoptiveLiquid BiopsyMolecular Targeted TherapyMutationNeoplasmsPrecision MedicineCell-Free Nucleic AcidscancercfDNAimmunotherapyNGStargeted therapy

Identifiers

PMID32806937
PMCPMC7791471

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.