Evidence map›Paper›PMID 32807179›Full record

Trial reportHealth and quality of life outcomes2020

High-intensity interval training and health-related quality of life in de novo heart transplant recipients - results from a randomized controlled trial.

Katrine Rolid, Arne K Andreassen, Marianne Yardley, Einar Gude, Elisabeth Bjørkelund, Anne R Authen, Ingelin Grov, Kjell I Pettersen, Christian H Dall, Kristjan Karason and 3 more

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Health and quality of life outcomes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01796379 (High Intensity Training in de Novo Heart Transplant Recipients in Scandinavia), which is not on this map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01796379 nacompletednot on this map

High Intensity Training in de Novo Heart Transplant Recipients in Scandinavia

TypeinterventionalSponsorOslo University HospitalRan2013 to 2019Enrolled80ConditionsHeart Transplant Recipients, Physical FitnessArmsHigh Intensity Interval Training, Moderate Training
3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it, 25 citations in OpenAlex.

  1. Rates of compliance and adherence to high-intensity interval training: a systematic review and Meta-analyses.The international journal of behavioral nutrition and physical activity · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 3 countries.

Katrine RolidDepartment of Cardiology, Oslo University Hospital Rikshospitalet, Rikshospitalet, , PO Box 4950 Nydalen, N-0424, Oslo, Norway. katrine.rolid@medisin.uio.no.ORCID http://orcid.org/0000-0003-0670-9312
Arne K AndreassenDepartment of Cardiology, Oslo University Hospital Rikshospitalet, Rikshospitalet, , PO Box 4950 Nydalen, N-0424, Oslo, Norway.
Marianne YardleyDepartment of Cardiology, Oslo University Hospital Rikshospitalet, Rikshospitalet, , PO Box 4950 Nydalen, N-0424, Oslo, Norway.
Einar GudeDepartment of Cardiology, Oslo University Hospital Rikshospitalet, Rikshospitalet, , PO Box 4950 Nydalen, N-0424, Oslo, Norway.
Elisabeth BjørkelundDepartment of Cardiology, Oslo University Hospital Rikshospitalet, Rikshospitalet, , PO Box 4950 Nydalen, N-0424, Oslo, Norway.
Anne R AuthenDepartment of Cardiology, Oslo University Hospital Rikshospitalet, Rikshospitalet, , PO Box 4950 Nydalen, N-0424, Oslo, Norway.
Ingelin GrovDepartment of Cardiology, Oslo University Hospital Rikshospitalet, Rikshospitalet, , PO Box 4950 Nydalen, N-0424, Oslo, Norway.
Kjell I PettersenDepartment of Cardiology, Oslo University Hospital Rikshospitalet, Rikshospitalet, , PO Box 4950 Nydalen, N-0424, Oslo, Norway.
Christian H DallDepartment of Cardiology, Bispebjerg University Hospital, Copenhagen, Denmark.
Kristjan KarasonTransplant Institute, Sahlgrenska University Hospital, Gothenburg, Sweden.
Kaspar BrochDepartment of Cardiology, Oslo University Hospital Rikshospitalet, Rikshospitalet, , PO Box 4950 Nydalen, N-0424, Oslo, Norway.
Lars GullestadDepartment of Cardiology, Oslo University Hospital Rikshospitalet, Rikshospitalet, , PO Box 4950 Nydalen, N-0424, Oslo, Norway.
Kari NytrøenDepartment of Cardiology, Oslo University Hospital Rikshospitalet, Rikshospitalet, , PO Box 4950 Nydalen, N-0424, Oslo, Norway.
Oslo University Hospital · NOBispebjerg Hospital · DKSahlgrenska University Hospital · SE

Funding

Helse Sør-Øst RHF 2013111Nasjonalforeningen for Folkehelsen 12906
6 · The paper itself

Abstract

backgroundStudies on the effect of high-intensity interval training (HIT) compared with moderate intensity continuous training (MICT) on health-related quality of life (HRQoL) after heart transplantation (HTx) is scarce. No available studies among de novo HTx recipients exists. This study aimed to investigate the effect of HIT vs. MICT on HRQoL in de novo recipients.

methodsThe HITTS study randomized eighty-one de novo HTx recipients to receive either HIT or MICT (1:1). The HIT intervention were performed with 2-4 interval bouts with an intensity of 85-95% of maximal effort. The MICT group exercised at an intensity of 60-80% of their maximal effort with a duration of 25 min. HRQoL was assessed by the Short Form-36 version 2 (SF-36v2) and the Hospital Anxiety and Depression Scale, mean 11 weeks after surgery and after a nine months' intervention. The participants recorded their subjective effect of the interventions on their general health and well-being on a numeric visual analogue scale. Clinical examinations and physical tests were performed. Differences between groups were investigated with independent Student t-tests and with Mann-Whitney U tests where appropriate. Within-group differences were analyzed with Paired-Sample t-tests and Wilcoxon Signed Rank tests. Correlations between SF-36 scores and VO

resultsSeventy-eight participants completed the intervention. Both exercise modes were associated with improved exercise capacity on the physical function scores of HRQoL. Mental health scores remained unchanged. No differences in the change in HRQoL between the groups occurred except for Role Emotional subscale with a larger increase in the HIT arm. Better self-reported physical function was associated with higher VO

conclusionHIT and MICT resulted in similar mean changes in HRQoL the first year after HTx. Both groups experienced significant improvements in the physical SF-36v2.

trial registrationClinicalTrials.gov number: NCT01796379 Registered 18 February 2013.

Indexed as

Quality of LifeAdultFemaleHeart TransplantationHigh-Intensity Interval TrainingHumansMaleMiddle AgedMuscle StrengthSelf ReportTransplant RecipientsExerciseHealth-related quality of lifeHeart transplantationHigh-intensity interval trainingModerate intensity continuous trainingMuscle strength,self-reported physical functionOxygen consumption

Identifiers

PMID32807179
PMCPMC7433122
OpenAlexW3074229566

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.