Evidence map›Paper›PMID 32809102›Full record

ArticleMolecular biology reports2020

Molecular process of glucose uptake and glycogen storage due to hamamelitannin via insulin signalling cascade in glucose metabolism.

Praveen Kumar Issac, Ajay Guru, Sri Snehaa Chandrakumar, Christy Lite, N T Saraswathi, Mariadhas Valan Arasu, Naif Abdullah Al-Dhabi, Aziz Arshad, Jesu Arockiaraj

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular biology reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.6field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 42 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 3 countries.

Praveen Kumar IssacSRM Research Institute, SRM Institute of Science and Technology, Kattankulathur, Chennai, Tamil Nadu, 603 203, India.ORCID http://orcid.org/0000-0003-3007-8792
Ajay GuruSRM Research Institute, SRM Institute of Science and Technology, Kattankulathur, Chennai, Tamil Nadu, 603 203, India.ORCID http://orcid.org/0000-0002-8583-9352
Sri Snehaa ChandrakumarDepartment of Biotechnology, Anna University, BIT Campus, Tiruchirappalli, Tamil Nadu, 620 024, India.ORCID http://orcid.org/0000-0002-7008-3521
Christy LiteEndocrine and Exposome Laboratory, Department of Zoology, Madras Christian College, Tambaram, Chennai, Tamil Nadu, 600 059, India.ORCID http://orcid.org/0000-0002-5797-1719
N T SaraswathiMolecular Biophysics Laboratory, School of Chemical and Biotechnology, SASTRA Deemed to be University, Thanjavur, Tamil Nadu, 613 401, India.ORCID http://orcid.org/0000-0002-9061-1571
Mariadhas Valan ArasuDepartment of Botany and Microbiology, College of Science, King Saud University, P.O. Box 2455, 11451, Riyadh, Saudi Arabia.ORCID http://orcid.org/0000-0001-5898-2121
Naif Abdullah Al-DhabiDepartment of Botany and Microbiology, College of Science, King Saud University, P.O. Box 2455, 11451, Riyadh, Saudi Arabia.ORCID http://orcid.org/0000-0002-2663-6328
Aziz ArshadInternational Institute of Aquaculture and Aquatic Sciences (I-AQUAS), Universiti Putra Malaysia, Port Dickson, Negeri Sembilan, 71050, Malaysia.ORCID http://orcid.org/0000-0002-8305-0833
Jesu ArockiarajSRM Research Institute, SRM Institute of Science and Technology, Kattankulathur, Chennai, Tamil Nadu, 603 203, India. jesuaraj@hotmail.com.ORCID http://orcid.org/0000-0002-0240-7141
SRM Institute of Science and Technology · INKing Saud University · SAAnna University, Chennai · INSASTRA University · INUniversiti Putra Malaysia · MY

Funding

Faculti Sains, Universiti Putra Malaysia LRGS/1/2019/UPM/1King Saud University RSP-2020/20
6 · The paper itself

Abstract

Understanding the mechanism by which the exogenous biomolecule modulates the GLUT-4 signalling cascade along with the information on glucose metabolism is essential for finding solutions to increasing cases of diabetes and metabolic disease. This study aimed at investigating the effect of hamamelitannin on glycogen synthesis in an insulin resistance model using L6 myotubes. Glucose uptake was determined using 2-deoxy-D-[1-

Indexed as

AnimalsBiological TransportCarbohydrate MetabolismCell SurvivalDiabetes Mellitus, Type 2Gallic AcidGenisteinGlucoseGlucose Transporter Type 4GlycogenGlycogen Synthase Kinase 3 betaHexosesInsulinInsulin AntagonistsInsulin ResistanceMuscle Fibers, SkeletalGallic AcidGenisteinGlucoseGlucose Transporter Type 4GlycogenGlycogen Synthase Kinase 3 betahamamelitanninHexosesInsulinInsulin Antagonistsinsulin receptor tyrosine kinasePhosphatidylinositol 3-KinasesProtein Kinase InhibitorsProtein-Tyrosine KinasesSlc2a4 protein, ratWortmanninGlycogen synthesisHamamelitanninInsulin signallingMolecular processType II diabetes mellitus

Identifiers

PMID32809102
OpenAlexW3050451847

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.