Evidence map›Paper›PMID 32811426›Full record

ArticleBMC cardiovascular disorders2020

Non-invasively measured central and peripheral factors of oxygen uptake differ between patients with chronic heart failure and healthy controls.

Joana Brochhagen, Michael Thomas Coll Barroso, Christian Baumgart, Jürgen Freiwald, Matthias Wilhelm Hoppe

Open access · goldAbstract read
In one paragraph

Article in BMC cardiovascular disorders, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Joana BrochhagenInstitute of Movement and Training Science I, University of Leipzig, Jahnallee 59, 04109, Leipzig, Germany. joana.brochhagen@uni-leipzig.de.ORCID 0000-0002-0992-6112
Michael Thomas Coll BarrosoHELIOS Klinikum Wuppertal, University of Witten/Herdecke, Heusnerstraße 40, 42283, Wuppertal, Germany.
Christian BaumgartDepartment of Movement and Training Science, University of Wuppertal, Fuhlrottstraße 10, 42119, Wuppertal, Germany.
Jürgen FreiwaldDepartment of Movement and Training Science, University of Wuppertal, Fuhlrottstraße 10, 42119, Wuppertal, Germany.
Matthias Wilhelm HoppeInstitute of Movement and Training Science I, University of Leipzig, Jahnallee 59, 04109, Leipzig, Germany.
University of Wuppertal · DEHelios Universitätsklinikum Wuppertal · DELeipzig University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMaximum oxygen uptake is an established measurement of diagnosing chronic heart failure and underlies various central and peripheral factors. However, central and peripheral factors are little investigated, because they are usually measured invasively. The aim of this study was to compare non-invasively measured central and peripheral factors of oxygen uptake between patients with chronic heart failure and healthy controls.

methodsTen male patients with heart failure with reduced ejection fraction (62 ± 4 years; body mass index: 27.7 ± 1.8 kg/m

resultsPatients had a likely to most likely lower oxygen uptake, mean arterial pressure, and heart rate at maximum load as well as very likely lower isometric peak torque. Contrary, patients had a possibly to likely higher stroke volume and muscle oxygen saturation of the vastus lateralis muscle at maximum load. Differences in cardiac output, cardiac power output, and muscle oxygen saturation of the biceps brachii muscle at maximum load were unclear.

conclusionsNon-invasively measured central and peripheral factors of oxygen uptake differ between patients with chronic heart failure and healthy controls. Therefore, it is promising to measure both types of factors in patients with chronic heart failure to optimize the diagnosis and therapy.

Indexed as

Exercise TestHemodynamicsIsometric ContractionMuscle StrengthOxygen ConsumptionSpectroscopy, Near-InfraredActivities of Daily LivingAgedCase-Control StudiesChronic DiseaseCross-Sectional StudiesHeart FailureHumansMaleMiddle AgedPredictive Value of TestsActivities of daily lifeAlternative statisticsArteriovenous oxygen differenceClinical practiceLactateQuestionnaireVariability

Identifiers

PMID32811426
PMCPMC7437074
OpenAlexW3065203473

What Socratic holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.