ArticleJournal of clinical hypertension (Greenwich, Conn.)2020
Muscle mass is the main somatic growth indicator associated with increasing blood pressure with age in children and adolescents.
Article in Journal of clinical hypertension (Greenwich, Conn.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed, 9 citations in OpenAlex.
- Anthropometric and Body Composition Correlates of Hypertension in Children and Adolescents with Intellectual Disabilities.Journal of clinical medicine · 2026Article
- Development of the Cardiovascular System During Adolescence.Advances in experimental medicine and biology · 2026Review
- Body composition predicts hypertension using machine learning methods: a cohort study.Scientific reports · 2023Article
- Effects of Crawling before Walking: Network Interactions and Longitudinal Associations in 7-Year-Old Children.International journal of environmental research and public health · 2022Article
- Muscle mass is the main somatic growth indicator associated with increasing blood pressure with age in children and adolescents.Journal of clinical hypertension (Greenwich, Conn.) · 2020Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Studies have shown that lean mass must be an important determinant of blood pressure value in children and adolescents. The absence of adjustment for the collinearity between lean and fat mass (FM), restricted age span, and lack of separate analysis by sex leave a gap in the literature. This study determined direct and indirect effects of the somatic growth indicators linked to the association between age and systolic blood pressure (SBP) in boys and girls. This is a cross-sectional study comprising 1,510 participants (6-18 years). Path analysis was used to test a model in which the association between age and SBP would have a direct and independent component, but also indirect mediating paths through muscle mass (MM), FM, and height. There was no significant association between age and SBP (unstandardized β ± SE) for both girls (0.072 ± 0.236, P = .761) and boys (0.238 ± 0.264, P = .368). Height was not a mediator for the association between age and SBP in both girls (-0.291 ± 0.156, P = .062) and boys (-0.015 ± 0.187, P = .935). Mediating effect of MM was significant for both girls (0.909 ± 0.137, P < .001) and boys (1.341 ± 0.161, P < .001), whereas mediating path through FM was significant only for boys (0.069 ± 0.023, P = .003). In conclusion, muscle mass was the strongest somatic growth indicator associated with the blood pressure value in children and adolescents. Further increase in body fat mass may affect systolic blood pressure more in boys than in girls.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.