Evidence map›Paper›PMID 32814451›Full record

ReviewHuman gene therapy2020

New Directions in Pulmonary Gene Therapy.

Amber Vu, Paul B McCray

Open access · greenAbstract readReview
In one paragraph

Review in Human gene therapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Review
  6. Progress in Respiratory Gene Therapy.Human gene therapy · 2022
    Review
  7. Review
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Amber VuStead Family Department of Pediatrics, Center for Gene Therapy, The University of Iowa, Iowa City, Iowa, USA.
Paul B McCrayStead Family Department of Pediatrics, Center for Gene Therapy, The University of Iowa, Iowa City, Iowa, USA.
University of Iowa · US

Funding

Respiratory virus infection in early cystic fibrosis lung diseaseP01HL091842 · NHLBI · UNIVERSITY OF IOWA · PI ZABNER, JOSEPH · 2008 to 2022
$34.2M
Vector Core-Core 2P30DK054759 · NIDDK · UNIVERSITY OF IOWA · PI Alejandro Antonio Pezzulo · 1998 to 2026
$30.5M
Pathology CoreP01HL152960 · NHLBI · UNIVERSITY OF IOWA · PI ENGELHARDT, JOHN F · 2020 to 2024
$11.6M
RESEARCH TRAINING IN INFECTIOUS DISEASEST32AI007343 · NIAID · UNIVERSITY OF IOWA · PI STAPLETON, JACK T. · 1988 to 2024
$5.0M
SCGE Disease Models Studies Supplement: Repair of a CFTR Nonsense Mutation Using Adenine Base EditingUH3HL147366 · NHLBI · UNIVERSITY OF IOWA · PI MCCRAY, PAUL B · 2021 to 2022
$2.3M
Delivery of CRISPR Ribonucleoproteins to Airway Epithelia Using Novel Amphiphilic PeptidesUG3HL147366 · NHLBI · UNIVERSITY OF IOWA · PI MCCRAY, PAUL B · 2018 to 2020
$2.1M
BLRD VA I01 BX000207NHLBI NIH HHS P01 HL091842NHLBI NIH HHS P01 HL152960NHLBI NIH HHS UG3 HL147366NHLBI NIH HHS UH3 HL147366NIAID NIH HHS T32 AI007343NIDDK NIH HHS P30 DK054759
6 · The paper itself

Abstract

The lung has long been a target for gene therapy, yet efficient delivery and phenotypic disease correction has remained challenging. Although there have been significant advancements in gene therapies of other organs, including the development of several

Indexed as

alpha 1-AntitrypsinCystic FibrosisCystic Fibrosis Transmembrane Conductance RegulatorDependovirusGene EditingGenetic TherapyGenetic VectorsHumansPulmonary Surfactant-Associated Protein Aalpha 1-AntitrypsinCFTR protein, humanCystic Fibrosis Transmembrane Conductance RegulatorPulmonary Surfactant-Associated Protein AAAVadenovirusCRISPR/Casgene editinglentivirus

Identifiers

PMID32814451
PMCPMC7495918
OpenAlexW3080948614

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.