Evidence map›Paper›PMID 32824065›Full record

ArticleNutrients2020

Protein Intake, Fatigue and Quality of Life in Stable Outpatient Kidney Transplant Recipients.

Antonio W Gomes Neto, Karin Boslooper-Meulenbelt, Marit Geelink, Iris M Y van Vliet, Adrian Post, Monica L Joustra, Hans Knoop, Stefan P Berger, Gerjan J Navis, Stephan J L Bakker

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03272841 (TransplantLines), which is not on this map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03272841 unknown statusnot on this map

TransplantLines: the Transplantation Biobank

Typeobservational_patient_registrySponsorUniversity Medical Center GroningenRan2015 to 2021Enrolled3,000ConditionsSolid Organ Tranplant Recipients, 18+ Years
3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 31 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Observational
  6. Sleep-Related Disorders in Patients with CKD and Kidney Transplant Recipients.Clinical journal of the American Society of Nephrology : CJASN · 2025
    Review
  7. Review
  8. Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Dietary Guidelines Post Kidney Transplant: Is This the Missing Link in Recovery and Graft Survival?Transplant international : official journal of the European Society for Organ Transplantation · 2025
    Review
  14. Correlation of objective and subjective sleep parameters with fatigue and depression in kidney transplant recipients.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2024
    Article
  15. Article
  16. Sleep quality, fatigue, societal participation and health-related quality of life in kidney transplant recipients: a cross-sectional and longitudinal cohort study.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2023
    Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Antonio W Gomes NetoDepartment of Internal Medicine, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.ORCID 0000-0002-4398-4877
Karin Boslooper-MeulenbeltDepartment of Internal Medicine, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.ORCID 0000-0001-6936-7853
Marit GeelinkDepartment of Internal Medicine, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.
Iris M Y van VlietDepartment of Dietetics, University Medical Center Groningen, 9700 RB Groningen, The Netherlands.
Adrian PostDepartment of Internal Medicine, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.ORCID 0000-0001-8645-1627
Monica L JoustraInterdisciplinary Center for Psychopathology and Emotion Regulation, University Medical Center Groningen, University of Groningen, 9700RB Groningen, The Netherlands.
Hans KnoopDepartment of Medical Psychology, Amsterdam University Medical Centers, University of Amsterdam, 1000 DD Amsterdam, The Netherlands.
Stefan P BergerDepartment of Internal Medicine, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.
Gerjan J NavisDepartment of Internal Medicine, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.
Stephan J L BakkerDepartment of Internal Medicine, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands.ORCID 0000-0003-3356-6791
University Medical Center Groningen · NLAmsterdam University Medical Centers · NL

Funding

Astellas Pharma, Netherlands N/A
6 · The paper itself

Abstract

Fatigue is a frequent complaint in kidney transplant recipients (KTR), often accompanied by poor quality of life (QoL). The role of nutrition as determinant of fatigue in KTR is largely unexplored. The aims of this study are to examine the association of protein intake with fatigue and QoL in KTR and to identify other determinants of fatigue. This cross-sectional study is part of the TransplantLines Cohort and Biobank Study (NCT03272841). Protein intake was calculated from urinary urea nitrogen (UUN) in 24-h urine samples. Fatigue was assessed by the Checklist Individual Strength (CIS) questionnaire; moderate and severe fatigue were defined as a CIS score of 20-34 and ≥ 35, respectively. QoL was assessed with the RAND-36-Item Health Survey (RAND-36). Associations of protein intake with fatigue and QoL were analyzed using multinomial logistic and linear regression analyses. We included 730 stable outpatient KTR (median age 58 year [IQR 48-65], 57% male) with a mean protein intake of 82.2 ± 21.3 g/d. Moderate and severe fatigue were present in 254 (35%) and 245 (34%) of KTR. Higher protein intake was significantly associated with lower risk of moderate fatigue (OR 0.89 per 10 g/d; 95%CI 0.83-0.98,

Indexed as

FatigueKidney TransplantationOutpatientsQuality of LifeAgedBody Mass IndexCholestyramine ResinCross-Sectional StudiesDietary ProteinsEatingFemaleGlomerulonephritisHumansHypocrealesMaleMiddle AgedCholestyramine ResinDietary Proteinsfatiguekidney transplantationnutritionproteinquality of life

Identifiers

PMID32824065
PMCPMC7469059
OpenAlexW3049481536

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.