Evidence mapPaperPMID 32824921Full record

ArticleInternational journal of molecular sciences2020

Reciprocal Dysregulation of MiR-146b and MiR-451 Contributes in Malignant Phenotype of Follicular Thyroid Tumor.

Margarita Knyazeva, Ekaterina Korobkina, Alexey Karizky, Maxim Sorokin, Anton Buzdin, Sergey Vorobyev, Anastasia Malek

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Attacking Cancer Progression and Metastasis.International journal of molecular sciences · 2023
    Article
  6. Article
  7. Article
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Margarita KnyazevaSubcellular technology Lab., N. N. Petrov National Medical Center of Oncology, 197758 Saint Petersburg, Russia.ORCID 0000-0002-2079-5061
Ekaterina KorobkinaSubcellular technology Lab., N. N. Petrov National Medical Center of Oncology, 197758 Saint Petersburg, Russia.
Alexey KarizkyInformation Technologies and Programming Faculty, Information Technologies, Mechanics and Optics (ITMO) University, 197101 Saint-Petersburg, Russia.
Maxim SorokinInstitute of Personalized Medicine, I.M. Sechenov First Moscow State Medical University, 119048 Moscow, Russia.
Anton BuzdinInstitute of Personalized Medicine, I.M. Sechenov First Moscow State Medical University, 119048 Moscow, Russia.
Sergey VorobyevNational Center of Clinical Morphological Diagnostics, 192283 Saint Petersburg, Russia.
Anastasia MalekSubcellular technology Lab., N. N. Petrov National Medical Center of Oncology, 197758 Saint Petersburg, Russia.ORCID 0000-0001-5334-7292

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Over the last few years, incidental thyroid nodules are being diagnosed with increasing frequency with the use of highly sensitive imaging techniques. The ultrasound thyroid gland examination, followed by the fine-needle aspiration cytology is the standard diagnostic approach. However, in cases of the follicular nature of nodules, cytological diagnosis is not enough. Analysis of miRNAs in the biopsy presents a promising approach. Increasing our knowledge of miRNA's role in follicular carcinogenesis, and development of the appropriate the miRNA analytical technologies are required to implement miRNA-based tests in clinical practice. We used material from follicular thyroid nodes (

Indexed as

Adenocarcinoma, FollicularBiomarkers, TumorFemaleHumansMaleMicroRNAsMiddle AgedNeoplasm InvasivenessPhenotypeThyroid NeoplasmsBiomarkers, TumorMicroRNAsMIRN146 microRNA, humanMIRN451 microRNA, humanfollicular adenomafollicular thyroid cancerinvasionmiRNAreciprocal dysregulationRT-qPCR

Identifiers

PMID32824921
PMCPMC7503510

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.