Evidence map›Paper›PMID 32826314›Full record

ArticleThe Journal of biological chemistry2020

Glycans function as a Golgi export signal to promote the constitutive exocytic trafficking.

Xiuping Sun, Hieng Chiong Tie, Bing Chen, Lei Lu

Open access · hybridAbstract read
In one paragraph

Article in The Journal of biological chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Mucin-typebioRxiv : the preprint server for biology · 2025
    Article
  5. Review
  6. Article
  7. Article
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  9. Article
  10. Cells · 2023
    Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Sending out molecules from the TGN.Current opinion in cell biology · 2021
    Review
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Xiuping SunSchool of Biological Sciences, Nanyang Technological University, Singapore.
Hieng Chiong TieSchool of Biological Sciences, Nanyang Technological University, Singapore.
Bing ChenSchool of Biological Sciences, Nanyang Technological University, Singapore.
Lei LuSchool of Biological Sciences, Nanyang Technological University, Singapore. Electronic address: lulei@ntu.edu.sg.
Nanyang Technological University · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Most proteins in the secretory pathway are glycosylated. However, the role of glycans in membrane trafficking is still unclear. Here, we discovered that transmembrane secretory cargos, such as interleukin 2 receptor α subunit or Tac, transferrin receptor, and cluster of differentiation 8a, unexpectedly displayed substantial Golgi localization when their

Indexed as

CD8 AntigensExocytosisGlycosylationGolgi ApparatusHeLa CellsHumansInterleukin-2 Receptor alpha SubunitPolysaccharidesProtein TransportReceptors, TransferrinCD8 antigen, alpha chainCD8 AntigensInterleukin-2 Receptor alpha SubunitPolysaccharidesReceptors, Transferrinconstitutive exocytosisexocytosisglycosylationGolgiGolgi exportGolgi localizationimagingintracellular traffickingmembrane proteinmembrane traffickingN-glycosylationO-glycosylationprotein trafficking (Golgi)secretory pathway

Identifiers

PMID32826314
PMCPMC7586228
OpenAlexW3081087801

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.