Evidence map›Paper›PMID 32831520›Full record

ArticleBioinformation2020

Views on GWAS statistical analysis.

Xiaowen Cao, Li Xing, Hua He, Xuekui Zhang

Open access · hybridAbstract read
In one paragraph

Article in Bioinformation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. 3D genomics and its applications in precision medicine.Cellular & molecular biology letters · 2023
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Xiaowen CaoDepartment of Mathematics, Hebei University of Technology, Tianjin, China.
Li XingDepartment of Mathematics and Statistics, University of Saskatchewan, Saskatoon, SK, Canada.
Hua HeDepartment of Mathematics, Hebei University of Technology, Tianjin, China.
Xuekui ZhangDepartment of Mathematics and Statistics, University of Victoria, BC, Canada.
University of Victoria · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Genome-wide association study (GWAS) is a popular approach to investigate relationships between genetic information and diseases. A number of associations are tested in a study and the results are often corrected using multiple adjustment methods. It is observed that GWAS studies suffer adequate statistical power for reliability. Hence, we document known models for reliability assessment using improved statistical power in GWAS analysis.

Indexed as

Genome-Wide Association StudiesLinkage DisequilibriumMultiple Testing AdjustmentSingle Nucleotide PolymorphismsStatistical powerSupervised LearningUnsupervised Learning

Identifiers

PMID32831520
PMCPMC7434950
OpenAlexW3018257973

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.