Evidence map›Paper›PMID 32833995›Full record

ArticlePloS one2020

Complications from percutaneous-left ventricular assist devices versus intra-aortic balloon pump in acute myocardial infarction-cardiogenic shock.

Saraschandra Vallabhajosyula, Anna V Subramaniam, Dennis H Murphree, Sri Harsha Patlolla, Lina Ya'Qoub, Vinayak Kumar, Dhiran Verghese, Wisit Cheungpasitporn, Jacob C Jentzer, Gurpreet S Sandhu and 6 more

Open access · goldAbstract readComparative Study
In one paragraph

Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
  2. Review
  3. Management of non-Cardiac Organ Failure in cardiogenic shock.American heart journal plus : cardiology research and practice · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Acute Kidney Injury in Cardiogenic Shock: An Updated Narrative Review.Journal of cardiovascular development and disease · 2021
    Review
  10. Article
  11. Article
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 6 institutions in 1 country.

Saraschandra VallabhajosyulaDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota, United States of America.ORCID 0000-0002-1631-8238
Anna V SubramaniamDepartment of Medicine, Mayo Clinic, Rochester, Minnesota, United States of America.ORCID 0000-0003-0077-8966
Dennis H MurphreeDepartment of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, United States of America.ORCID 0000-0002-7800-455X
Sri Harsha PatlollaDepartment of Cardiovascular Surgery, Mayo Clinic, Rochester, Minnesota, United States of America.
Lina Ya'QoubDivision of Cardiovascular Medicine, Department of Medicine, Louisiana State University School of Medicine, Shreveport, Louisiana, United States of America.
Vinayak KumarDepartment of Medicine, Mayo Clinic, Rochester, Minnesota, United States of America.
Dhiran VergheseDepartment of Medicine, Amita Health Saint Joseph Hospital, Chicago, Illinois, United States of America.
Wisit CheungpasitpornDivision of Nephrology, Department of Medicine, University of Mississippi School of Medicine, Jackson, Mississippi, United States of America.
Jacob C JentzerDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota, United States of America.
Gurpreet S SandhuDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota, United States of America.
Rajiv GulatiDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota, United States of America.
Nilay D ShahDepartment of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, United States of America.
Bernard J GershDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota, United States of America.
David R HolmesDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota, United States of America.ORCID 0000-0002-0037-0373
Malcolm R BellDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota, United States of America.
Gregory W BarsnessDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, Minnesota, United States of America.
Mayo Clinic · USAmita Health · USLouisiana State University in Shreveport · USMayo Clinic in Arizona · USMayo Clinic in Florida · USUniversity of Mississippi · US

Funding

Mayo Clinic Center for Translational Science ActivitiesUL1TR000135 · NCATS · MAYO CLINIC ROCHESTER · PI KHOSLA, SUNDEEP · 2012 to 2015
$41.2M
NCATS NIH HHS UL1 TR000135
6 · The paper itself

Abstract

backgroundThere are limited data on the complications with a percutaneous left ventricular assist device (pLVAD) vs. intra-aortic balloon pump (IABP) in acute myocardial infarction-cardiogenic shock (AMI-CS).

objectiveTo assess the trends, rates and predictors of complications.

methodsUsing a 17-year AMI-CS population from the National Inpatient Sample, AMI-CS admissions receiving pLVAD and IABP support were evaluated for vascular, lower limb amputation, hematologic, neurologic and acute kidney injury (AKI) complications. In-hospital mortality, hospitalization costs and length of stay in pLVAD and IABP cohorts with complications was studied.

resultsOf 168,645 admissions, 7,855 (4.7%) receiving pLVAD support. The pLVAD cohort had higher comorbidity, cardiac arrest (36.1% vs. 29.7%) and non-cardiac organ failure (74.7% vs. 56.9%) rates. Complications were higher in pLVAD compared to IABP cohort-overall 69.0% vs. 54.7%; vascular 3.8% vs. 2.1%; lower limb amputation 0.3% vs. 0.3%; hematologic 36.0% vs. 27.7%; neurologic 4.9% vs. 3.5% and AKI 55.4% vs. 39.1% (all p<0.001 except for amputation). Non-White race, higher comorbidity, organ failure, and extracorporeal membrane oxygen use were predictors of complications for both cohorts. The pLVAD cohort with complications had higher in-hospital mortality (45.5% vs. 33.1%; adjusted odds ratio 1.65 [95% confidence interval 1.55-1.75]), shorter duration of hospital stay, and higher hospitalization costs compared to the IABP cohort with complications (all p<0.001). These results were consistent in propensity-matched pairs.

conclusionsAMI-CS admissions receiving pLVAD had higher rates of complications compared to the IABP, with worse in-hospital outcomes in the cohort with complications.

Indexed as

Acute DiseaseAgedFemaleHeart-Assist DevicesHospitalsHumansIntra-Aortic Balloon PumpingMaleMiddle AgedMyocardial InfarctionPostoperative ComplicationsShock, Cardiogenic

Identifiers

PMID32833995
PMCPMC7444810
OpenAlexW3080316984

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.