Evidence map›Paper›PMID 32842497›Full record

SynthesisNutrients2020

The Effects of Cow-Milk Protein Supplementation in Elderly Population: Systematic Review and Narrative Synthesis.

Barbara Zanini, Anna Simonetto, Matilde Zubani, Maurizio Castellano, Gianni Gilioli

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 4 pooled it
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 4 syntheses or guidelines pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Observational
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Barbara ZaniniDepartment of Clinical and Experimental Sciences, University of Brescia, Viale Europa, 11, I-25123 Brescia, Italy.ORCID 0000-0002-1733-9938
Anna SimonettoAgroFood Lab, Department of Molecular and Translational Medicine, University of Brescia, Viale Europa, 11, I-25123 Brescia, Italy.ORCID 0000-0003-1291-5569
Matilde ZubaniAgroFood Lab, Department of Molecular and Translational Medicine, University of Brescia, Viale Europa, 11, I-25123 Brescia, Italy.
Maurizio CastellanoDepartment of Clinical and Experimental Sciences, University of Brescia, Viale Europa, 11, I-25123 Brescia, Italy.
Gianni GilioliAgroFood Lab, Department of Molecular and Translational Medicine, University of Brescia, Viale Europa, 11, I-25123 Brescia, Italy.
University of Brescia · IT

Funding

AOP Latte Italia NA
6 · The paper itself

Abstract

backgroundTo review currently available evidence on the effect of cow-milk proteins supplementation (CPS) on health in the elderly.

methodsFive electronic databases (Pubmed, Web of Science, Embase, Cochrane Library, ClinicalTrials.gov) were searched for studies about CPS among older people. All types of publications were included, with the exception of systematic reviews, meta-analyses, opinion letters, editorials, case reports, conference abstracts and comments. An additional search in Google Scholar and a manual review of the reference lists were performed.

resultsOverall, 103 studies were included. Several studies explored the role of CPS in the preservation or improvement of muscle mass among healthy subjects (40 studies) and pre-frail, frail or sarcopenic patients (14), with evidence of beneficial effects. Other studies assessed the effect of CPS on bones (12), cardiovascular disease (8), inflamm-aging (7), chronic pulmonary disease (4), neurocognitive function (4), and vaccines (2), with weak evidence of positive effects. Seven studies in the field of protein metabolism investigated the role of CPS as an important contributor to nutritional needs. Other investigational areas are considered in the last five studies.

conclusionsThe beneficial effects of CPS in achieving aged-related nutritional goals, in preserving muscle mass and in recovering after hospitalization may be particularly relevant in the elderly.

Indexed as

AgedAnimalsDietary SupplementsFrailtyHumansMilkMilk ProteinsMuscle, SkeletalMuscle StrengthSarcopeniaMilk Proteinscaseinmuscle massnutritionolder peoplesarcopeniawhey protein

Identifiers

PMID32842497
PMCPMC7551861
OpenAlexW3081469194

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.