Evidence map›Paper›PMID 32842509›Full record

ArticleMolecules (Basel, Switzerland)2020

Drug Repurposing for Candidate SARS-CoV-2 Main Protease Inhibitors by a Novel

Milan Sencanski, Vladimir Perovic, Snezana B Pajovic, Miroslav Adzic, Slobodan Paessler, Sanja Glisic

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed.

  1. Article
  2. Article
  3. SARS-CoV-2 PLChemistryOpen · 2024
    Article
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  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Milan SencanskiLaboratory of Bioinformatics and Computational Chemistry, Institute of Nuclear Sciences Vinca, National Institute of the Republic of Serbia, University of Belgrade, 11001 Belgrade, Serbia.
Vladimir PerovicLaboratory of Bioinformatics and Computational Chemistry, Institute of Nuclear Sciences Vinca, National Institute of the Republic of Serbia, University of Belgrade, 11001 Belgrade, Serbia.
Snezana B PajovicDepartment of Molecular Biology and Endocrinology, VINCA Institute of Nuclear Sciences, National Institute of the Republic of Serbia, University of Belgrade, 11001 Belgrade, Serbia.
Miroslav AdzicDepartment of Molecular Biology and Endocrinology, VINCA Institute of Nuclear Sciences, National Institute of the Republic of Serbia, University of Belgrade, 11001 Belgrade, Serbia.
Slobodan PaesslerDepartment of Pathology, University of Texas Medical Branch, Galveston, TX 77555, USA.
Sanja GlisicLaboratory of Bioinformatics and Computational Chemistry, Institute of Nuclear Sciences Vinca, National Institute of the Republic of Serbia, University of Belgrade, 11001 Belgrade, Serbia.

Funding

Ministarstvo Prosvete, Nauke i Tehnološkog Razvoja -
6 · The paper itself

Abstract

The SARS-CoV-2 outbreak caused an unprecedented global public health threat, having a high transmission rate with currently no drugs or vaccines approved. An alternative powerful additional approach to counteract COVID-19 is

Indexed as

Allosteric SiteAntiviral AgentsBetacoronavirusCatalytic DomainCoronavirus 3C ProteasesCoronavirus InfectionsCOVID-19Cysteine EndopeptidasesDrug RepositioningGene ExpressionHigh-Throughput Screening AssaysHumansMezlocillinMolecular Docking SimulationPandemicsPneumonia, ViralAntiviral AgentsCoronavirus 3C ProteasesCysteine EndopeptidasesMezlocillinProtease InhibitorsRaltegravir PotassiumViral Nonstructural Proteinsdrug repurposingISMmain protease MproSARS-CoV-2virtual screening

Identifiers

PMID32842509
PMCPMC7503980

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.