Evidence map›Paper›PMID 32847965›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2020

Direct Observation of Vesicle Transport on the Synaptic Ribbon Provides Evidence That Vesicles Are Mobilized and Prepared Rapidly for Release.

Christina Joselevitch, David Zenisek

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 27 citations in OpenAlex.

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  17. Transmission at rod and cone ribbon synapses in the retina.Pflugers Archiv : European journal of physiology · 2021
    Review
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Christina JoselevitchDepartment of Cellular and Molecular Physiology, Yale University School of Medicine, New Haven, Connecticut 06511.
David ZenisekDepartment of Cellular and Molecular Physiology, Yale University School of Medicine, New Haven, Connecticut 06511 david.zenisek@yale.edu.
Universidade de São Paulo · BRYale University · US

Funding

CELLULAR NEUROPHYSIOLOGY OF THE VERTEBRATE RETINAR01EY003821 · NEI · STATE UNIVERSITY NEW YORK STONY BROOK · PI WOLLMUTH, LONNIE P · 1985 to 2019
$8.1M
Yale Core Grant for Vision ResearchP30EY026878 · NEI · YALE UNIVERSITY · PI Jonathan B Demb · 2016 to 2026
$7.1M
Investigating the Role of Ribeye in Retinal Ribbon FunctionR01EY021195 · NEI · YALE UNIVERSITY · PI ZENISEK, DAVID PAUL · 2011 to 2019
$3.3M
NEI NIH HHS P30 EY026878NEI NIH HHS R01 EY003821NEI NIH HHS R01 EY021195
6 · The paper itself

Abstract

Synaptic ribbons are thought to provide vesicles for continuous release in some retinal nonspiking neurons, yet recent studies indicate that genetic removal of the ribbon has little effect on release kinetics. To investigate vesicle replenishment at synaptic ribbons, we used total internal reflection fluorescence microscopy to image synaptic vesicles and ribbons in retinal bipolar cells of goldfish (

Indexed as

ExocytosisSynaptic PotentialsAnimalsCells, CulturedFemaleGoldfishMaleNeuronal PlasticityNeuronsSynaptic Vesiclesbipolar cellsretinaribbon synapsessynaptic depressionTIRF microscopyvesicle release

Identifiers

PMID32847965
PMCPMC7511195
OpenAlexW3081450209

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.