Evidence mapPaperPMID 32848859Full record

ReviewFrontiers in physiology2020

Current and Emerging Topical Scar Mitigation Therapies for Craniofacial Burn Wound Healing.

Sun Hyung Kwon, Janos A Barrera, Chikage Noishiki, Kellen Chen, Dominic Henn, Clifford C Sheckter, Geoffrey C Gurtner

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Sun Hyung KwonDepartment of Surgery, Stanford University School of Medicine, Stanford, CA, United States.
Janos A BarreraDepartment of Surgery, Stanford University School of Medicine, Stanford, CA, United States.
Chikage NoishikiDepartment of Surgery, Stanford University School of Medicine, Stanford, CA, United States.
Kellen ChenDepartment of Surgery, Stanford University School of Medicine, Stanford, CA, United States.
Dominic HennDepartment of Surgery, Stanford University School of Medicine, Stanford, CA, United States.
Clifford C SheckterDepartment of Surgery, Stanford University School of Medicine, Stanford, CA, United States.
Geoffrey C GurtnerDepartment of Surgery, Stanford University School of Medicine, Stanford, CA, United States.
Stanford University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Burn injury in the craniofacial region causes significant health and psychosocial consequences and presents unique reconstructive challenges. Healing of severely burned skin and underlying soft tissue is a dynamic process involving many pathophysiological factors, often leading to devastating outcomes such as the formation of hypertrophic scars and debilitating contractures. There are limited treatment options currently used for post-burn scar mitigation but recent advances in our knowledge of the cellular and molecular wound and scar pathophysiology have allowed for development of new treatment concepts. Clinical effectiveness of these experimental therapies is currently being evaluated. In this review, we discuss current topical therapies for craniofacial burn injuries and emerging new therapeutic concepts that are highly translational.

Indexed as

burn injuryburn physiologydrug therapyfacial burnwound healing

Identifiers

PMID32848859
PMCPMC7403506
OpenAlexW3045789423

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.