ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2022
Prediction of appropriate ICD therapy in patients with ischemic heart failure.
Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.
- The prognostic value ofJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022Pooled it
- Energy spectrum-based correction of washout rates in dual-isotopeAnnals of nuclear medicine · 2026Article
- The neuronal imaging in cardiology: 123I-Biophysical reviews · 2025Review
- Predicting postinfarct ventricular tachycardia by integrating cardiac MRI and advanced computational reentrant pathway analysis.Heart rhythm · 2024Article
- Ischemic cardiomyopathy: epidemiology, pathophysiology, outcomes, and therapeutic options.Heart failure reviews · 2024Review
- Optimal Protocol and Clinical Usefulness ofNuclear medicine and molecular imaging · 2023Article
- Review of cardiovascular imaging in the Journal of Nuclear Cardiology 2022: single photon emission computed tomography.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023Review
- The value of cardiac sympathetic activity and mechanical dyssynchrony as cardiac resynchronization therapy response predictors: comparison between patients with ischemic and non-ischemic heart failure.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023Article
- CardiacJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022Article
- CardiacPharmaceuticals (Basel, Switzerland) · 2022Review
- Importance of individual patient characteristics when assessing the ability of cardiac adrenergic imaging to guide ICD use.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022Article
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPrevious studies show inconsistent results on the role of innervation imaging (with I-123-mIBG) and perfusion imaging in predicting appropriate ICD therapy (aICDth). These studies included patients with both dilated and ischemic cardiomyopathy. This study compared the ability of
methodsmIBG/thallium SPECT imaging were performed before ICD implantation in 80 patients with IHF: 49 candidates for primary and 31 for secondary SCD prevention.
resultsDuring a mean follow-up of 18 months, the imaging results could not predict patients with appropriate ICD therapy among patients with ICD implants for primary SCD prevention. While in the secondary SCD prevention group, those who received a ICDth had significantly larger summed scores of regional perfusion and innervation impairment, but not higher heart-to-mediastinal mIBG ratio. The best results to predict aICDth were using mIBG summed score (cut-off point > 34%, sensitivity 72%, specificity 100%, AUC 0.909, P < 0.0001).
conclusionThe prognostic value of innervation and perfusion imaging in patients with IHF differ based on indication for ICD implantation (primary vs. secondary prevention of SCD).
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