Evidence map›Paper›PMID 32869093›Full record

ArticleJournal of the American Medical Informatics Association : JAMIA2020

Predicting complications of diabetes mellitus using advanced machine learning algorithms.

Branimir Ljubic, Ameen Abdel Hai, Marija Stanojevic, Wilson Diaz, Daniel Polimac, Martin Pavlovski, Zoran Obradovic

Open access · greenAbstract readComparative Study
In one paragraph

Article in Journal of the American Medical Informatics Association : JAMIA, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 2 pooled it
5.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 2 syntheses or guidelines pooled it, 73 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Branimir LjubicCenter for Data Analytics and Biomedical Informatics, Temple University, Philadelphia, Pennsylvania, USA.
Ameen Abdel HaiCenter for Data Analytics and Biomedical Informatics, Temple University, Philadelphia, Pennsylvania, USA.
Marija StanojevicCenter for Data Analytics and Biomedical Informatics, Temple University, Philadelphia, Pennsylvania, USA.
Wilson DiazCenter for Data Analytics and Biomedical Informatics, Temple University, Philadelphia, Pennsylvania, USA.
Daniel PolimacCenter for Data Analytics and Biomedical Informatics, Temple University, Philadelphia, Pennsylvania, USA.
Martin PavlovskiCenter for Data Analytics and Biomedical Informatics, Temple University, Philadelphia, Pennsylvania, USA.
Zoran ObradovicCenter for Data Analytics and Biomedical Informatics, Temple University, Philadelphia, Pennsylvania, USA.
Temple University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveWe sought to predict if patients with type 2 diabetes mellitus (DM2) would develop 10 selected complications. Accurate prediction of complications could help with more targeted measures that would prevent or slow down their development. MATERIALS AND

methodsExperiments were conducted on the Healthcare Cost and Utilization Project State Inpatient Databases of California for the period of 2003 to 2011. Recurrent neural network (RNN) long short-term memory (LSTM) and RNN gated recurrent unit (GRU) deep learning methods were designed and compared with random forest and multilayer perceptron traditional models. Prediction accuracy of selected complications were compared on 3 settings corresponding to minimum number of hospitalizations between diabetes diagnosis and the diagnosis of complications.

resultsThe diagnosis domain was used for experiments. The best results were achieved with RNN GRU model, followed by RNN LSTM model. The prediction accuracy achieved with RNN GRU model was between 73% (myocardial infarction) and 83% (chronic ischemic heart disease), while accuracy of traditional models was between 66% - 76%. DISCUSSION: The number of hospitalizations was an important factor for the prediction accuracy. Experiments with 4 hospitalizations achieved significantly better accuracy than with 2 hospitalizations. To achieve improved accuracy deep learning models required training on at least 1000 patients and accuracy significantly dropped if training datasets contained 500 patients. The prediction accuracy of complications decreases over time period. Considering individual complications, the best accuracy was achieved on depressive disorder and chronic ischemic heart disease.

conclusionsThe RNN GRU model was the best choice for electronic medical record type of data, based on the achieved results.

Indexed as

AlgorithmsDeep LearningDiabetes ComplicationsDecision TreesDiabetes Mellitus, Type 2HumansNeural Networks, ComputerPrognosisRisk Assessmentdeep learningdiabetes mellitusdiabetes mellitus complicationsmachine learningRNN models

Identifiers

PMID32869093
PMCPMC7647294
OpenAlexW3082762715

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.