Evidence map›Paper›PMID 32869956›Full record

Trial reportPhysiological reports2020

Impact of a weight loss and fitness intervention on exercise-associated plasma oxylipin patterns in obese, insulin-resistant, sedentary women.

Dmitry Grapov, Oliver Fiehn, Caitlin Campbell, Carol J Chandler, Dustin J Burnett, Elaine C Souza, Gretchen A Casazza, Nancy L Keim, Gary R Hunter, Jose R Fernandez and 5 more

Open access · goldAbstract readClinical Trial
In one paragraph

Trial report in Physiological reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 28 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 8 institutions in 3 countries.

Dmitry GrapovCDS-Creative Data Solutions, Davis, CA, USA.
Oliver FiehnWest Coast Metabolomics Center, University of California, Davis, CA, USA.
Caitlin CampbellUnited States Department of Agriculture-Agricultural Research Service Western Human Nutrition Research Center, Davis, CA, USA.
Carol J ChandlerUnited States Department of Agriculture-Agricultural Research Service Western Human Nutrition Research Center, Davis, CA, USA.
Dustin J BurnettUnited States Department of Agriculture-Agricultural Research Service Western Human Nutrition Research Center, Davis, CA, USA.
Elaine C SouzaUnited States Department of Agriculture-Agricultural Research Service Western Human Nutrition Research Center, Davis, CA, USA.
Gretchen A CasazzaDepartment of Kinesiology, California State University, Sacramento, CA, USA.
Nancy L KeimUnited States Department of Agriculture-Agricultural Research Service Western Human Nutrition Research Center, Davis, CA, USA.
Gary R HunterDepartment of Nutrition Sciences, University of Alabama, Birmingham, AL, USA.
Jose R FernandezDepartment of Nutrition Sciences, University of Alabama, Birmingham, AL, USA.
W Timothy GarveyDepartment of Nutrition Sciences, University of Alabama, Birmingham, AL, USA.
Charles L HoppelPharmacology Department, Case Western Reserve University, Cleveland, OH, USA.
Mary-Ellen HarperDepartment of Biochemistry, Microbiology and Immunology, and Ottawa Institute of Systems Biology, University of Ottawa, Ottawa, ON, Canada.
John W NewmanUnited States Department of Agriculture-Agricultural Research Service Western Human Nutrition Research Center, Davis, CA, USA.
Sean H AdamsArkansas Children's Nutrition Center, Little Rock, AR, USA.ORCID 0000-0002-9515-2319
Agricultural Research Service · USUniversity of Alabama at Birmingham · USArkansas Children's Nutrition Center · USCalifornia State University, Sacramento · USCase Western Reserve University · USTa Solutions (China) · CNUniversity of California, Davis · USUniversity of Ottawa · CA

Funding

Why is the prevalence of obesity so high in U.S. Southern States? Regional predictors of BMI and obesity treatment response.P30DK056336 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI BARBARA A GOWER · 2000 to 2026
$31.9M
University of Alabama at Birmingham's Diabetes Research CenterP30DK079626 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI BARBARA A GOWER · 2013 to 2026
$19.5M
West Coast Central Comprehensive Metabolomics Resource Core (WC3MRC)U24DK097154 · NIDDK · UNIVERSITY OF CALIFORNIA AT DAVIS · PI FIEHN, OLIVER · 2012 to 2017
$9.9M
Identification of Muscle-Specific Biomarkers of Fatty Acid beta-OxidationR01DK078328 · NIDDK · U.S. AGRICULTURAL RESEARCH SERVICE · PI ADAMS, SEAN HARRISON · 2008 to 2012
$1.8M
NIDDK NIH HHS P30 DK056336NIDDK NIH HHS P30 DK079626NIDDK NIH HHS R01 DK078328NIDDK NIH HHS R01DK078328NIDDK NIH HHS U24 DK097154NIH HHS U24DK097154
6 · The paper itself

Abstract

Very little is known about how metabolic health status, insulin resistance or metabolic challenges modulate the endocannabinoid (eCB) or polyunsaturated fatty acid (PUFA)-derived oxylipin (OxL) lipid classes. To address these questions, plasma eCB and OxL concentrations were determined at rest, 10 and 20 min during an acute exercise bout (30 min total, ~45% of preintervention V̇O

Indexed as

AdultCytochrome P-450 CYP2J2Cytochrome P-450 Enzyme SystemEpoxide HydrolasesExercise TherapyFemaleHumansInsulin ResistanceLinoleic AcidLipoxygenaseMiddle AgedObesityOxylipinsSedentary BehaviorWeight Reduction ProgramsCytochrome P-450 CYP2J2Cytochrome P-450 Enzyme SystemEPHX2 protein, humanEpoxide HydrolasesLinoleic AcidLipoxygenaseOxylipinslipoxygenaseoxylipidpolyunsaturated fatty acidPUFAsoluble epoxide hydrolase

Identifiers

PMID32869956
PMCPMC7460071
OpenAlexW3082677324

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.