Evidence map›Paper›PMID 32878211›Full record

ArticleDiagnostics (Basel, Switzerland)2020

Molecular Changes in Tissue Proteome during Prostate Cancer Development: Proof-of-Principle Investigation.

Agnieszka Latosinska, Katarina Davalieva, Manousos Makridakis, William Mullen, Joost P Schanstra, Antonia Vlahou, Harald Mischak, Maria Frantzi

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.5field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 5 countries.

Agnieszka LatosinskaMosaiques Diagnostics GmbH, 30659 Hannover, Germany.
Katarina DavalievaResearch Centre for Genetic Engineering and Biotechnology "Georgi D Efremov", Macedonian Academy of Sciences and Arts, 1000 Skopje, North Macedonia.ORCID 0000-0002-0878-6533
Manousos MakridakisBiomedical Research Foundation of the Academy of Athens, Centre of Systems Biology, 11527 Athens, Greece.
William MullenInstitute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow G12 8QQ, UK.ORCID 0000-0002-5685-1563
Joost P SchanstraInstitut National de la Santé et de la Recherche Médicale (INSERM), U1048, Institute of Cardiovascular and Metabolic Diseases, 31432 Toulouse, France.
Antonia VlahouBiomedical Research Foundation of the Academy of Athens, Centre of Systems Biology, 11527 Athens, Greece.
Harald MischakMosaiques Diagnostics GmbH, 30659 Hannover, Germany.
Maria FrantziMosaiques Diagnostics GmbH, 30659 Hannover, Germany.ORCID 0000-0003-0415-0316
Mosaiques Diagnostics and Therapeutics (Germany) · DEBiomedical Research Foundation of the Academy of Athens · GRMacedonian Academy of Sciences and Arts · MKUniversité Toulouse III - Paul Sabatier · FRUniversity of Glasgow · GB

Funding

H2020 Marie Skłodowska-Curie Actions 800048
6 · The paper itself

Abstract

(1) Background: Prostate cancer (PCa) is characterized by high heterogeneity. The aim of this study was to investigate molecular alterations underlying PCa development based on proteomics data. (2) Methods: Liquid chromatography coupled to tandem mass spectrometry was conducted for 22 fresh-frozen tissue specimens from patients with benign prostatic hyperplasia (BPH,

Indexed as

drug targetpersonalized medicineprostate cancerproteomicstissue

Identifiers

PMID32878211
PMCPMC7554904
OpenAlexW3081988424

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.