Evidence map›Paper›PMID 32887498›Full record

ArticleInternational journal of molecular sciences2020

Decreased Urinary Levels of

Olga Martinez-Arroyo, Ana Ortega, Miriam Galera, Elena Solaz, Sergio Martinez-Hervas, Josep Redon, Raquel Cortes

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. NADCell communication and signaling : CCS · 2024
    Review
  7. Ability of NAD and Sirt1 to epigenetically suppress albuminuria.Clinical and experimental nephrology · 2024
    Review
  8. Article
  9. Article
  10. The sirtuin family in health and disease.Signal transduction and targeted therapy · 2022
    Review
  11. Article
  12. Editorial of Special Issue "Sirtuins in Health and Disease".International journal of molecular sciences · 2021
    Article
  13. Frontiers in pharmacology · 2021
    Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Olga Martinez-ArroyoCardiometabolic and Renal Risk Research Group, INCLIVA Biomedical Research Institute, 46010 Valencia, Spain.ORCID 0000-0001-9602-8419
Ana OrtegaCardiometabolic and Renal Risk Research Group, INCLIVA Biomedical Research Institute, 46010 Valencia, Spain.ORCID 0000-0002-9763-0505
Miriam GaleraCardiometabolic and Renal Risk Research Group, INCLIVA Biomedical Research Institute, 46010 Valencia, Spain.
Elena SolazCardiometabolic and Renal Risk Research Group, INCLIVA Biomedical Research Institute, 46010 Valencia, Spain.
Sergio Martinez-HervasService of Endocrinology and Nutrition, Hospital Clinico Universitario, 46010 Valencia, Spain.ORCID 0000-0002-6775-2034
Josep RedonCardiometabolic and Renal Risk Research Group, INCLIVA Biomedical Research Institute, 46010 Valencia, Spain.ORCID 0000-0001-8777-6773
Raquel CortesCardiometabolic and Renal Risk Research Group, INCLIVA Biomedical Research Institute, 46010 Valencia, Spain.ORCID 0000-0001-9607-997X
INCLIVA Health Research Institute · ESHospital Clínico Universitario de Valencia · ESInstituto de Salud Carlos III · ESUniversitat de València · ES

Funding

European Regional Development Fund ERDFInstituto de Salud Carlos III PI12/02615; PI18/01405; PI19/01796 (FIS Projects) and CD18/00166
6 · The paper itself

Abstract

Sirtuins have become important players in renal damage in hypertension and diabetes, but their value as biomarkers is poorly assessed. The aims of the study were to evaluate the levels of sirtuin1 (SIRT1), and two miRNAs that regulate SIRT1 expression in hypertensive patients with incipient renal damage with and without diabetes. We quantified urinary

Indexed as

BiomarkersClaudin-1FemaleHumansHypertensionKidney DiseasesMaleMicroRNAsMiddle AgedPodocytesSirtuin 1UrinalysisBiomarkersClaudin-1CLDN1 protein, humanMicroRNAsMIRN200 microRNA, humanMIRN34 microRNA, humanSIRT1 protein, humanSirtuin 1claudin 1diabetes mellitushypertensionmiRNApodocytesirtuin 1urinary albumin excretion

Identifiers

PMID32887498
PMCPMC7503821
OpenAlexW3081567884

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.