Evidence map›Paper›PMID 32894097›Full record

ArticleBMC psychiatry2020

The role of trauma experiences, personality traits, and genotype in maintaining posttraumatic stress disorder symptoms among child survivors of the Wenchuan earthquake.

Yuwei Li, Qiuyue Lv, Bin Li, Dan Luo, Xueli Sun, Jiajun Xu

Open access · goldAbstract read
In one paragraph

Article in BMC psychiatry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Yuwei LiMental Health Center, West China Hospital, Sichuan University, Chengdu, China.
Qiuyue LvMental Health Center, West China Hospital, Sichuan University, Chengdu, China.
Bin LiMental Health Center, West China Hospital, Sichuan University, Chengdu, China.
Dan LuoMental Health Center, West China Hospital, Sichuan University, Chengdu, China.
Xueli SunMental Health Center, West China Hospital, Sichuan University, Chengdu, China. sunxuelihx@163.com.
Jiajun XuMental Health Center, West China Hospital, Sichuan University, Chengdu, China. xujiajun120@126.com.ORCID 0000-0002-3260-383X
Sichuan University · CN

Funding

National Natural Science Foundation of China 81401132Sichuan Provincial Science and Technology Support Program 2019YFS0218
6 · The paper itself

Abstract

backgroundPosttraumatic stress disorder (PTSD) is the most prevalent type of psychiatric disorder among children after an earthquake. This study investigated the role of trauma experiences, personality traits, and genotype in the maintenance of PTSD symptoms.

methodsIn a previous large-scale epidemiological investigation 1 year after the Wenchuan earthquake, 215 children with PTSD symptoms were selected at random with their blood samples collected. All of them were followed up, and their PTSD symptoms were assessed 3 years later. The adolescent version of the UCLA PTSD Reaction Index, the earthquake exposure scale, and the Junior Eysenck Personality Questionnaire were used to determine PTSD symptoms, trauma experiences, and personality traits, respectively. We sequenced candidate genes involved in the regulation of long-term potentiation via NMDA-type receptors to identify the related SNP variations.

resultsBeing trapped for a longer period of time, feeling one's own or a family member's life to be in danger, losing a close family member or friend, extraversion, neuroticism, TrkB, G72 and CNTF were found to be associated with the maintenance of PTSD symptoms.

conclusionsExperiences, personality traits, and genotype influenced the maintenance of PTSD in child survivors who were considered to be followed up without medicine. This result could help to identify potential targets for treatment and promote the rational allocation of medical resources.

Indexed as

EarthquakesStress Disorders, Post-TraumaticAdolescentChildChinaFamilyGenotypeHumansMaintenanceRisk FactorsSurvivorsChildrenEarthquakeLong-term potentiationPersonality traitsPosttraumatic stress disorder

Identifiers

PMID32894097
PMCPMC7487586
OpenAlexW3084202365

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.