Evidence map›Paper›PMID 32902979›Full record

ArticleThe journal of physical chemistry. B2020

Temperature-Jump 2D IR Spectroscopy with Intensity-Modulated CW Optical Heating.

Brennan Ashwood, Nicholas H C Lewis, Paul J Sanstead, Andrei Tokmakoff

Open access · greenAbstract read
In one paragraph

Article in The journal of physical chemistry. B, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
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  12. Increasing Pump-Probe Signal toward Asymptotic Limits.The journal of physical chemistry. B · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Brennan AshwoodDepartment of Chemistry, James Franck Institute, and Institute for Biophysical Dynamics, The University of Chicago, Chicago, Illinois 60637, United States.ORCID 0000-0001-7614-6071
Nicholas H C LewisDepartment of Chemistry, James Franck Institute, and Institute for Biophysical Dynamics, The University of Chicago, Chicago, Illinois 60637, United States.ORCID 0000-0002-2554-0199
Paul J SansteadDepartment of Chemistry, James Franck Institute, and Institute for Biophysical Dynamics, The University of Chicago, Chicago, Illinois 60637, United States.
Andrei TokmakoffDepartment of Chemistry, James Franck Institute, and Institute for Biophysical Dynamics, The University of Chicago, Chicago, Illinois 60637, United States.ORCID 0000-0002-2434-8744
Chicago Institute for Psychoanalysis · US

Funding

The Dynamics of Molecular Recognition by Proteins from 2D IR Spectroscopy and MD SimulationsR01GM118774 · NIGMS · UNIVERSITY OF CHICAGO · PI TOKMAKOFF, ANDREI · 2016 to 2019
$1.6M
NIGMS NIH HHS R01 GM118774
6 · The paper itself

Abstract

Pulsed temperature-jump (T-jump) spectroscopy with infrared (IR) detection has been widely used to study biophysical processes occurring from nanoseconds to ∼1 ms with structural sensitivity. However, many systems exhibit structural dynamics on time scales longer than the millisecond barrier that is set by the time scale for thermal relaxation of the sample. We developed a linear and nonlinear infrared spectrometer coupled to an intensity-modulated continuous wave (CW) laser to probe T-jump-initiated chemical reactions from <1 ms to seconds. Time-dependent modulation of the CW laser leads to a <1 ms heating time as well as a constant final temperature (±3%) for the duration of the heating time. Temperature changes of up to 75 °C in D

Indexed as

UbiquitinHot TemperatureKineticsSpectrophotometry, InfraredTemperatureUbiquitin

Identifiers

PMID32902979
PMCPMC7850621
OpenAlexW3084109089

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.