Evidence map›Paper›PMID 32903598›Full record

ArticleFrontiers in immunology2020

S100A8 and S100A9 Promote Apoptosis of Chronic Eosinophilic Leukemia Cells.

Ji-Sook Lee, Na Rae Lee, Ayesha Kashif, Seung-Ju Yang, A Reum Nam, Ik-Chan Song, Soo-Jung Gong, Min Hwa Hong, Geunyeong Kim, Pu Reum Seok and 3 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
3.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 30 citations in OpenAlex.

  1. Diagnostic Value of Synovial Fluid Biomarkers for Periprosthetic Joint Infection: A Prospective, Double-blind Trial.Medical science monitor : international medical journal of experimental and clinical research · 2023
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  8. S100A8 and S100A9 in Hematologic Malignancies: From Development to Therapy.International journal of molecular sciences · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 1 country.

Ji-Sook LeeDepartment of Clinical Laboratory Science, Wonkwang Health Science University, Iksan, South Korea.
Na Rae LeeDepartment of Biomedical Laboratory Science, Eulji University School of Medicine, Daejeon, South Korea.
Ayesha KashifDepartment of Senior Healthcare, BK21 Plus Program, Graduate School, Eulji University, Daejeon, South Korea.
Seung-Ju YangDepartment of Biomedical Laboratory Science, Konyang University, Daejeon, South Korea.
A Reum NamDepartment of Biomedical Laboratory Science, Konyang University, Daejeon, South Korea.
Ik-Chan SongDivision of Hematology/Oncology, Department of Internal Medicine, Chungnam National University School of Medicine, Chungnam National University Hospital, Daejeon, South Korea.
Soo-Jung GongDepartment of Internal Medicine, Eulji Medical Center, Eulji University School of Medicine, Daejeon, South Korea.
Min Hwa HongDepartment of Senior Healthcare, BK21 Plus Program, Graduate School, Eulji University, Daejeon, South Korea.
Geunyeong KimDepartment of Senior Healthcare, BK21 Plus Program, Graduate School, Eulji University, Daejeon, South Korea.
Pu Reum SeokDepartment of Senior Healthcare, BK21 Plus Program, Graduate School, Eulji University, Daejeon, South Korea.
Myung-Shin LeeDepartment of Microbiology and Immunology, Eulji University School of Medicine, Daejeon, South Korea.
Kee-Hyung SungDepartment of Senior Healthcare, BK21 Plus Program, Graduate School, Eulji University, Daejeon, South Korea.
In Sik KimDepartment of Biomedical Laboratory Science, Eulji University School of Medicine, Daejeon, South Korea.
Eulji University · KRChungnam National University Hospital · KRKonyang University · KRSeoul National University · KRWonKwang Health Science University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

S100A8 and S100A9 function as essential factors in inflammation and also exert antitumor or tumorigenic activity depending on the type of cancer. Chronic eosinophilic leukemia (CEL) is a rare hematological malignancy having elevated levels of eosinophils and characterized by the presence of the

Indexed as

ApoptosisAnimalsCalgranulin ACalgranulin BCell Line, TumorCells, CulturedChronic DiseaseDrug Resistance, NeoplasmFemaleGene ExpressionHumansHypereosinophilic SyndromeImatinib MesylateMiceMitochondriaModels, BiologicalCalgranulin ACalgranulin BImatinib MesylateProtein Kinase InhibitorsReceptor, Platelet-Derived Growth Factor alphaRecombinant ProteinsS100A8 protein, humanS100A9 protein, humanchronic eosinophilic leukemiaFIP1L1-PDGFRαimatinib resistanceS100 proteinTLR4

Identifiers

PMID32903598
PMCPMC7438788
OpenAlexW3049095668

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.