ArticleScientific reports2020
Usefulness of heart rhythm complexity in heart failure detection and diagnosis.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
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Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Heart Rate Variability and Coronary Artery Bypass Grafting: A Systematic Review.Reviews in cardiovascular medicine · 2024Pooled it
- Temporal Changes in Nonlinear Heart Rate Variability Following Pulmonary Vein Isolation for Paroxysmal Atrial Fibrillation.Acta Cardiologica Sinica · 2026Article
- Complexity of Nuclear States forEntropy (Basel, Switzerland) · 2026Article
- Autonomic impairment in advanced heart-failure patients revealed by nonlinear heart rate variability measured during exercise.Scientific reports · 2026Article
- Circadian Activity Disruption in Cardiac Remodeling Patients Underlies Autonomic Dysfunction in Heart Failure.Biomedicines · 2026Article
- Harnessing Nonlinear Mechanics to Transform Medical Diagnostics.Applied mechanics reviews · 2025Article
- Association of Vitamin D Deficiency With Abnormal Electrocardiographic Activity Among Healthy People.Food science & nutrition · 2025Review
- Heart Rate Variability Analysis in Congestive Heart Failure: The Need for Standardized Assessment Protocols.Reviews in cardiovascular medicine · 2025Review
- Heart Rate Recovery: Up to Date in Heart Failure-A Literature Review.Journal of clinical medicine · 2024Review
- [Exploratory study on quantitative analysis of nocturnal breathing patterns in patients with acute heart failure based on wearable devices].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2023Article
- Heart Rate Variability Measurement through a Smart Wearable Device: Another Breakthrough for Personal Health Monitoring?International journal of environmental research and public health · 2023Review
- Modifications of long-term heart rate variability produced in an experimental model of diet-induced metabolic syndrome.Interface focus · 2023Article
- Heart rhythm complexity analysis in patients with inferior ST-elevation myocardial infarction.Scientific reports · 2023Article
- Skin sympathetic nerve activity as a biomarker for outcomes in spontaneous intracerebral hemorrhage.Annals of clinical and translational neurology · 2023Article
- Effects of Acute Hypoxia on Heart Rate Variability in Patients with Pulmonary Vascular Disease.Journal of clinical medicine · 2023Article
- A two-step pre-processing tool to remove Gaussian and ectopic noise for heart rate variability analysis.Scientific reports · 2022Article
- Nonlinear Heart Rate Dynamics Before and After Paroxysmal Atrial Fibrillation Events.Acta Cardiologica Sinica · 2022Article
- The autonomic balance of heart rhythm complexity after renal artery denervation: insight from entropy of entropy and average entropy analysis.Biomedical engineering online · 2022Article
- Heart Rate Variability from Wearable Photoplethysmography Systems: Implications in Sleep Studies at High Altitude.Sensors (Basel, Switzerland) · 2022Article
- Reduced System Complexity of Heart Rate Dynamics in Patients with Hyperthyroidism: A Multiscale Entropy Analysis.Entropy (Basel, Switzerland) · 2022Article
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Authors and funding
10 authors.
Funding
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Abstract
Heart failure (HF) is a major cardiovascular disease worldwide, and the early detection and diagnosis remain challenges. Recently, heart rhythm complexity analysis, derived from non-linear heart rate variability (HRV) analysis, has been proposed as a non-invasive method to detect diseases and predict outcomes. In this study, we aimed to investigate the diagnostic value of heart rhythm complexity in HF patients. We prospectively analyzed 55 patients with symptomatic HF with impaired left ventricular ejection fraction and 97 participants without HF symptoms and normal LVEF as controls. Traditional linear HRV parameters and heart rhythm complexity including detrended fluctuation analysis (DFA) and multiscale entropy (MSE) were analyzed. The traditional linear HRV, MSE parameters and DFAα1 were significantly lower in HF patients compared with controls. In regression analysis, DFAα1 and MSE scale 5 remained significant predictors after adjusting for multiple clinical variables. Among all HRV parameters, MSE scale 5 had the greatest power to differentiate the HF patients from the controls in receiver operating characteristic curve analysis (area under the curve: 0.844). In conclusion, heart rhythm complexity appears to be a promising tool for the detection and diagnosis of HF.
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