Evidence mapPaperPMID 32916976Full record

ReviewMedicina (Kaunas, Lithuania)2020

Endometriosis Associated Infertility: A Critical Review and Analysis on Etiopathogenesis and Therapeutic Approaches.

Lidia Filip, Florentina Duică, Alina Prădatu, Dragoș Crețoiu, Nicolae Suciu, Sanda Maria Crețoiu, Dragoș-Valentin Predescu, Valentin Nicolae Varlas, Silviu-Cristian Voinea

Open access · goldAbstract readReview
In one paragraph

Review in Medicina (Kaunas, Lithuania), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 1 pooled it
10.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 1 synthesis or guideline pooled it, 112 citations in OpenAlex.

  1. Pooled it
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  5. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Lidia FilipAlessandrescu-Rusescu National Institute for Mother and Child Health, Fetal Medicine Excellence Research Center, 020395 Bucharest, Romania.
Florentina DuicăAlessandrescu-Rusescu National Institute for Mother and Child Health, Fetal Medicine Excellence Research Center, 020395 Bucharest, Romania.
Alina PrădatuAlessandrescu-Rusescu National Institute for Mother and Child Health, Fetal Medicine Excellence Research Center, 020395 Bucharest, Romania.
Dragoș CrețoiuAlessandrescu-Rusescu National Institute for Mother and Child Health, Fetal Medicine Excellence Research Center, 020395 Bucharest, Romania.ORCID 0000-0003-3214-030X
Nicolae SuciuAlessandrescu-Rusescu National Institute for Mother and Child Health, Fetal Medicine Excellence Research Center, 020395 Bucharest, Romania.
Sanda Maria CrețoiuDepartment of Cell and Molecular Biology and Histology, "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.ORCID 0000-0003-2575-4880
Dragoș-Valentin PredescuDepartment of General Surgery, Sf. Maria Clinical Hospital, "Carol Davila" University of Medicine and Pharmacy, 011172 Bucharest, Romania.
Valentin Nicolae VarlasDepartment of Obstetrics and Gynecology, Filantropia Clinical Hospital, 01171 Bucharest, Romania.
Silviu-Cristian VoineaDepartment of Surgical Oncology, Alexandru Trestioreanu Oncology Institute, "Carol Davila" University of Medicine and Pharmacy, 022328 Bucharest, Romania.
Carol Davila University of Medicine and Pharmacy · ROInstitutul National pentru Sanatatea Mamei si Copilului "Alessandrescu-Rusescu" · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endometriosis represents a frequently diagnosed gynecological affliction in the reproductive timespan of women, defined by symptoms ranging from pelvic pain to infertility. A complex interplay between the genetic profile, hormonal activity, menstrual cyclicity, inflammation status, and immunological factors define the phenotypic presentation of endometriosis. To date, imaging techniques represent the gold standard in diagnosing endometriosis, of which transvaginal ultrasonography and magnetic resonance imaging bring the most value to the diagnostic step. Current medical treatment options for endometriosis-associated infertility focus on either stimulating the follicular development and ovulation or on inhibiting the growth and development of endometriotic lesions. Techniques of assisted reproduction consisting of superovulation with in vitro fertilization or intrauterine insemination represent effective treatment alternatives that improve fertility in patients suffering from endometriosis. Emerging therapies such as the usage of antioxidant molecules and stem cells still need future research to prove the therapeutic efficacy in this pathology.

Indexed as

EndometriosisInfertility, FemaleDiagnostic Tests, RoutineFemaleFertilization in VitroHumansReproductive Techniques, Assistedendometriosisetiopathogenesisinfertilityin vitro fertilizationtreatment

Identifiers

PMID32916976
PMCPMC7559069
OpenAlexW3083948149

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.