Evidence map›Paper›PMID 32922929›Full record

ReviewChinese neurosurgical journal2019

Scavenger Receptor Class B type 1 (SR-B1) and the modifiable risk factors of stroke.

Cameron Lenahan, Lei Huang, Zachary D Travis, John H Zhang

Open access · diamondAbstract readReview
In one paragraph

Review in Chinese neurosurgical journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Knobs, Adhesion, and Severe Falciparum Malaria.Tropical medicine and infectious disease · 2023
    Review
  7. Review
  8. Nutrients · 2022
    Article
  9. Review
  10. Inflammation: A New Look at an Old Problem.International journal of molecular sciences · 2022
    Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Cameron LenahanBurrell College of Osteopathic Medicine, Las Cruces, NM 88003 USA.
Lei HuangCenter for Neuroscience Research, School of Medicine, Loma Linda University, Loma Linda, CA 92324 USA.
Zachary D TravisCenter for Neuroscience Research, School of Medicine, Loma Linda University, Loma Linda, CA 92324 USA.
John H ZhangCenter for Neuroscience Research, School of Medicine, Loma Linda University, Loma Linda, CA 92324 USA.
Loma Linda University · US

Funding

Cerebrospinal Fluid Dynamics in Posthemorrhagic Hydrocephalus in NeonatesR01NS103822 · NINDS · LOMA LINDA UNIVERSITY · PI ZHANG, JOHN H · 2017 to 2021
$1.7M
NINDS NIH HHS R01 NS103822
6 · The paper itself

Abstract

Stroke is a devastating disease that occurs when a blood vessel in the brain is either blocked or ruptured, consequently leading to deficits in neurological function. Stroke consistently ranked as one of the top causes of mortality, and with the mean age of incidence decreasing, there is renewed interest to seek novel therapeutic treatments. The Scavenger Receptor Class B type 1 (SR-B1) is a multifunctional protein found on the surface of a variety of cells. Research has found that that SR-B1 primarily functions in an anti-inflammatory and anti-atherosclerotic capacity. In this review, we discuss the characteristics of SR-B1 and focus on its potential correlation with the modifiable risk factors of stroke. SR-B1 likely has an impact on stroke through its interaction with smoking, diabetes mellitus, diet, physical inactivity, obesity, hypercholesterolemia, atherosclerosis, coronary heart disease, hypertension, and sickle cell disease, all of which are critical risk factors in the pathogenesis of stroke.

Indexed as

AtherosclerosisCoronary heart diseaseDiabetes mellitusHypercholesterolemiaHypertensionObesityPhysical inactivityScavenger Receptor Class B type 1Sickle cellSR-B1

Identifiers

PMID32922929
PMCPMC7398188
OpenAlexW2995850801

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.