ReviewMolecules (Basel, Switzerland)2020
Molecules Isolated from Mexican Hypoglycemic Plants: A Review.
Review in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
12 citing papers in PubMed, 32 citations in OpenAlex.
- Antidiabetic Properties of the Tropical TreePharmaceuticals (Basel, Switzerland) · 2025Review
- Hypoglycemic and Hypolipidemic Effects of Triterpenoid Standardized Extract ofPlants (Basel, Switzerland) · 2025Article
- Research progress on the anti-cancer mechanisms of edible salty-flavored Chinese materia medica.Frontiers in pharmacology · 2025Review
- Effect ofInternational journal of molecular sciences · 2024Article
- Phytochemical Screening and Isolation of NewPlants (Basel, Switzerland) · 2022Article
- Selected Species of the Cucurbitaceae Family Used in Mexico for the Treatment of Diabetes Mellitus.Molecules (Basel, Switzerland) · 2022Review
- Antidiabetic Sterols fromACS omega · 2022Article
- Chronic Antihyperglycemic Effect Exerted by Traditional Extracts of Three Mexican Medicinal Plants.Evidence-based complementary and alternative medicine : eCAM · 2022Article
- Hypoglycemic Effect of Two Mexican Medicinal Plants.Plants (Basel, Switzerland) · 2021Article
- Contributions from Mexican Flora for the Treatment of Diabetes Mellitus: Molecules ofMolecules (Basel, Switzerland) · 2021Review
- Article
- Cheminformatics to Characterize Pharmacologically Active Natural Products.Biomolecules · 2020Review
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Like in many developing countries, in Mexico, the use of medicinal plants is a common practice. Based on our own field experience, there are at least 800 plants used for treating diabetes nowadays. Thus, their investigation is essential. In this context, this work aims to provide a comprehensive and critical review of the molecules isolated from Mexican hypoglycemic plants, including their source and target tested. In the last few years, some researchers have focused on the study of Mexican hypoglycemic plants. Most works describe the hypoglycemic effect or the mechanism of action of the whole extract, as well as the phytochemical profile of the tested extract. Herein, we analyzed 85 studies encompassing 40 hypoglycemic plants and 86 active compounds belonging to different classes of natural products: 28 flavonoids, 25 aromatic compounds, other than flavonoids, four steroids, 23 terpenoids, 4 oligosaccharides, and 1 polyalcohol. These compounds have shown to inhibit α-glucosidases, increase insulin secretion levels, increase insulin sensitivity, and block hepatic glucose output. Almost half of these molecules are not common metabolites, with a narrow taxonomic distribution, which makes them more interesting as lead molecules. Altogether, this analysis provides a necessary inventory useful for future testing of these active molecules against different hypoglycemic targets, to get a better insight into the already described mechanisms, and overall, to contribute to the knowledge of Mexican medicinal plants.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.