ArticleScientific reports2020
Humic acid enhances heat stress tolerance via transcriptional activation of Heat-Shock Proteins in Arabidopsis.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 62 citations in OpenAlex.
- The transcriptional cascade CiERF023Horticulture research · 2026Article
- Defining the Molecular Impacts of Humalite Application on Field-Grown Wheat (Triticum aestivum L.) Using Quantitative Proteomics.Proteomics · 2025Article
- Structure-Based Function of Humic Acid in Abiotic Stress Alleviation in Plants: A Review.Plants (Basel, Switzerland) · 2025Review
- Chemical application improves stress resilience in plants.Plant molecular biology · 2025Review
- The Genetics and Breeding of Heat Stress Tolerance in Wheat: Advances and Prospects.Plants (Basel, Switzerland) · 2025Review
- Analysis of Plant Physiological Parameters and Gene Transcriptional Changes Under the Influence of Humic Acid and Humic Acid-Amino Acid Combinations in Maize.International journal of molecular sciences · 2024Article
- Impact of exogenous rhamnolipids on plant photosynthesis and biochemical parameters under prolonged heat stress.Photosynthetica · 2024Article
- Next generation plant biostimulants & genome sequencing strategies for sustainable agriculture development.Frontiers in microbiology · 2024Review
- Maize heat shock proteins-prospection, validation, categorization and in silico analysis of the different ZmHSP families.Stress biology · 2023Article
- Salt and drought stress-mitigating approaches in sugar beet (Beta vulgaris L.) to improve its performance and yield.Planta · 2023Review
- High-throughput identification of novel heat tolerance genes via genome-wide pooled mutant screens in the model green alga Chlamydomonas reinhardtii.Plant, cell & environment · 2023Article
- Role of Agricultural Management in the Provision of Ecosystem Services in Warm Climate Vineyards: Functional Prediction of Genes Involved in Nutrient Cycling and Carbon Sequestration.Plants (Basel, Switzerland) · 2023Article
- Comparative transcriptional and co-expression network analysis of two upland cotton accessions with extreme phenotypic differences reveals molecular mechanisms of fiber development.Frontiers in plant science · 2023Article
- Analysis of basic pentacysteine6 transcription factor involved in abiotic stress response inFrontiers in genetics · 2023Article
- Enhancing crop resilience by harnessing the synergistic effects of biostimulants against abiotic stress.Frontiers in plant science · 2023Review
- Proteomic Analysis of Barley (Plants (Basel, Switzerland) · 2022Article
- Strategies and prospects for biostimulants to alleviate abiotic stress in plants.Frontiers in plant science · 2022Review
- Recent Advances in the Molecular Effects of Biostimulants in Plants: An Overview.Biomolecules · 2021Review
- Transcriptome Changes Reveal the Molecular Mechanisms of Humic Acid-Induced Salt Stress Tolerance in Arabidopsis.Molecules (Basel, Switzerland) · 2021Article
- Which Traits of Humic Substances Are Investigated to Improve Their Agronomical Value?Molecules (Basel, Switzerland) · 2021Article
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Humic acid (HA) is composed of a complex supramolecular association and is produced by humification of organic matters in soil environments. HA not only improves soil fertility, but also stimulates plant growth. Although numerous bioactivities of HA have been reported, the molecular evidences have not yet been elucidated. Here, we performed transcriptomic analysis to identify the HA-prompted molecular mechanisms in Arabidopsis. Gene ontology enrichment analysis revealed that HA up-regulates diverse genes involved in the response to stress, especially to heat. Heat stress causes dramatic induction in unique gene families such as Heat-Shock Protein (HSP) coding genes including HSP101, HSP81.1, HSP26.5, HSP23.6, and HSP17.6A. HSPs mainly function as molecular chaperones to protect against thermal denaturation of substrates and facilitate refolding of denatured substrates. Interestingly, wild-type plants grown in HA were heat-tolerant compared to those grown in the absence of HA, whereas Arabidopsis HSP101 null mutant (hot1) was insensitive to HA. We also validated that HA accelerates the transcriptional expression of HSPs. Overall, these results suggest that HSP101 is a molecular target of HA promoting heat-stress tolerance in Arabidopsis. Our transcriptome information contributes to understanding the acquired genetic and agronomic traits by HA conferring tolerance to environmental stresses in plants.
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