Evidence map›Paper›PMID 32930949›Full record

SynthesisEndocrine2021

Association between metabolic syndrome and gestational diabetes mellitus in women and their children: a systematic review and meta-analysis.

Maleesa M Pathirana, Zohra S Lassi, Anna Ali, Margaret A Arstall, Claire T Roberts, Prabha H Andraweera

Registry-linked trialAbstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Endocrine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06704035 (Early Screening for Gestational Diabetes Mellitus in a Low Risk Population), which is not on this map. Cited by 42 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 4 pooled it
2.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06704035 nanot yet recruitingnot on this mapstarted 2024, after this paper: background citation

Early Screening for Gestational Diabetes Mellitus in a Low Risk Population

TypeinterventionalSponsorNational University Hospital, SingaporeRan2024 to 2026Enrolled120ConditionsGestational Diabetes Mellitus (GDM), Glucose Intolerance During PregnancyArmsEarly OGTT Results Revealed
3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 4 syntheses or guidelines pooled it, 69 citations in OpenAlex.

  1. Gestational Diabetes Mellitus and Adverse Maternal and Neonatal Health Outcomes: an Umbrella review of Meta-Analyses.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Maleesa M PathiranaAdelaide Medical School and Robinson Research Institute, The University of Adelaide, Adelaide, SA, 5005, Australia.
Zohra S LassiAdelaide Medical School and Robinson Research Institute, The University of Adelaide, Adelaide, SA, 5005, Australia.
Anna AliHealth Performance and Policy Research Unit, Basil Hetzel Institute, The University of Adelaide, Adelaide, SA, Australia.
Margaret A ArstallFaculty of Health and Medical Sciences, Adelaide Medical School, The University of Adelaide, Adelaide, SA, Australia.
Claire T RobertsAdelaide Medical School and Robinson Research Institute, The University of Adelaide, Adelaide, SA, 5005, Australia.
Prabha H AndraweeraAdelaide Medical School and Robinson Research Institute, The University of Adelaide, Adelaide, SA, 5005, Australia. prabha.andraweera@adelaide.edu.au.ORCID http://orcid.org/0000-0003-2434-8370
Lyell McEwin Hospital · AUThe University of Adelaide · AUBasil Hetzel Institute · AUFlinders University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe primary aim of this systematic review and meta-analysis was to determine the association between gestational diabetes mellitus (GDM) and metabolic syndrome (MetS) in women and children. Our secondary aim was to assess the development of MetS with respect to the elapsed time postpartum at which MetS was diagnosed.

methodsThis review is registered with PROSPERO (CRD42020173319). PubMed, CINHAL, SCOPUS, and EMBASE databases were searched. Studies reporting on the rate of MetS in pregnant women with GDM, the rate of MetS in women with a history of GDM, and the rate of MetS in offspring exposed to GDM in utero compared to healthy controls were selected.

resultsWe identified 588 articles from the literature search. Fifty-one studies were included in the review and of those 35 were included in the meta-analysis. Quantitative summary measures showed that women with a history of GDM had an increased risk of developing MetS compared to those without a history of GDM (RR 2.36, 95% CI 1.77-3.14, 29 studies, 13,390 participants; heterogeneity: χ CONCLUSIONS/

interpretationWomen with GDM have an increased risk of developing MetS during pregnancy. Women with a history of GDM and offspring exposed to GDM in utero have higher risks of developing MetS compared to those with no history of GDM. Metabolic syndrome in women with a history of GDM is seen as early as <1 year postpartum.

Indexed as

Diabetes, GestationalMetabolic SyndromeChildFemaleHumansPostpartum PeriodPregnancyRisk FactorsChildhood obesityGestational diabetesMetabolic syndromeWomen’s health

Identifiers

PMID32930949
OpenAlexW3086787446

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.