Evidence map›Paper›PMID 32932589›Full record

ArticleJournal of personalized medicine2020

Transcript Levels of Aldo-Keto Reductase Family 1 Subfamily C (AKR1C) Are Increased in Prostate Tissue of Patients with Type 2 Diabetes.

Andras Franko, Lucia Berti, Jörg Hennenlotter, Steffen Rausch, Marcus O Scharpf, Martin Hrabĕ de Angelis, Arnulf Stenzl, Andreas L Birkenfeld, Andreas Peter, Stefan Z Lutz and 2 more

Open access · goldAbstract read
In one paragraph

Article in Journal of personalized medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.8field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Andras FrankoDepartment of Internal Medicine IV, Division of Endocrinology, Diabetology and Nephrology, University Hospital Tübingen, 72076 Tübingen, Germany.ORCID 0000-0003-0485-5439
Lucia BertiInstitute for Diabetes Research and Metabolic Diseases, Helmholtz Centre Munich, University of Tübingen, 72076 Tübingen, Germany.ORCID 0000-0003-4264-5096
Jörg HennenlotterDepartment of Urology, University Hospital Tübingen, 72076 Tübingen, Germany.ORCID 0000-0003-3827-6996
Steffen RauschDepartment of Urology, University Hospital Tübingen, 72076 Tübingen, Germany.ORCID 0000-0002-6398-8701
Marcus O ScharpfInstitute of Pathology, University Hospital Tübingen, 72076 Tübingen, Germany.
Martin Hrabĕ de AngelisGerman Center for Diabetes Research (DZD), 85764 Neuherberg, Germany.
Arnulf StenzlDepartment of Urology, University Hospital Tübingen, 72076 Tübingen, Germany.
Andreas L BirkenfeldDepartment of Internal Medicine IV, Division of Endocrinology, Diabetology and Nephrology, University Hospital Tübingen, 72076 Tübingen, Germany.
Andreas PeterInstitute for Diabetes Research and Metabolic Diseases, Helmholtz Centre Munich, University of Tübingen, 72076 Tübingen, Germany.
Stefan Z LutzDepartment of Internal Medicine IV, Division of Endocrinology, Diabetology and Nephrology, University Hospital Tübingen, 72076 Tübingen, Germany.
Hans-Ulrich HäringDepartment of Internal Medicine IV, Division of Endocrinology, Diabetology and Nephrology, University Hospital Tübingen, 72076 Tübingen, Germany.
Martin HeniDepartment of Internal Medicine IV, Division of Endocrinology, Diabetology and Nephrology, University Hospital Tübingen, 72076 Tübingen, Germany.
University Children's Hospital Tübingen · DEDeutsches Diabetes-Zentrum e.V. · DEHelmholtz Zentrum München · DE

Funding

DZD e.V.
6 · The paper itself

Abstract

Aldo-keto reductase family 1 (AKR1) enzymes play a crucial role in diabetic complications. Since type 2 diabetes (T2D) is associated with cancer progression, we investigated the impact of diabetes on

Indexed as

aldo-keto reductase family 1diabetesHIF1aNFkBprostate cancer

Identifiers

PMID32932589
PMCPMC7564141
OpenAlexW3085774860

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.