Evidence map›Paper›PMID 32932733›Full record

Trial reportNutrients2020

Whole Blueberry and Isolated Polyphenol-Rich Fractions Modulate Specific Gut Microbes in an In Vitro Colon Model and in a Pilot Study in Human Consumers.

Alexandra Ntemiri, Tarini S Ghosh, Molly E Gheller, Tam T T Tran, Jamie E Blum, Paola Pellanda, Klara Vlckova, Marta C Neto, Amy Howell, Anna Thalacker-Mercer and 1 more

Abstract readClinical Trial
In one paragraph

Trial report in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Trial
  4. Trial
  5. Trial
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Dietary Intake and Gut Microbiome in CKD.Clinical journal of the American Society of Nephrology : CJASN · 2025
    Review
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Aging and Inflammation.Cold Spring Harbor perspectives in medicine · 2024
    Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Alexandra NtemiriSchool of Microbiology, University College Cork, T12 K8AF Cork, Ireland.ORCID 0000-0002-8742-0627
Tarini S GhoshSchool of Microbiology, University College Cork, T12 K8AF Cork, Ireland.
Molly E GhellerDivision of Nutritional Sciences, Cornell University, Ithaca, NY 14853, USA.
Tam T T TranSchool of Microbiology, University College Cork, T12 K8AF Cork, Ireland.
Jamie E BlumDivision of Nutritional Sciences, Cornell University, Ithaca, NY 14853, USA.ORCID 0000-0002-2168-5390
Paola PellandaSchool of Microbiology, University College Cork, T12 K8AF Cork, Ireland.
Klara VlckovaSchool of Microbiology, University College Cork, T12 K8AF Cork, Ireland.
Marta C NetoSchool of Microbiology, University College Cork, T12 K8AF Cork, Ireland.
Amy HowellMarucci Center for Blueberry Cranberry Research, Rutgers University, Chatsworth, NJ 08019, USA.ORCID 0000-0002-8069-7017
Anna Thalacker-MercerDivision of Nutritional Sciences, Cornell University, Ithaca, NY 14853, USA.
Paul W O'TooleSchool of Microbiology, University College Cork, T12 K8AF Cork, Ireland.

Funding

National Science Foundation Graduate Research Fellowship Program DGE-1650441
6 · The paper itself

Abstract

Blueberry (BB) consumption is linked to improved health. The bioconversion of the polyphenolic content of BB by fermentative bacteria in the large intestine may be a necessary step for the health benefits attributed to BB consumption. The identification of specific gut microbiota taxa that respond to BB consumption and that mediate the bioconversion of consumed polyphenolic compounds into bioactive forms is required to improve our understanding of how polyphenols impact human health. We tested the ability of polyphenol-rich fractions purified from whole BB-namely, anthocyanins/flavonol glycosides (ANTH/FLAV), proanthocyanidins (PACs), the sugar/acid fraction (S/A), and total polyphenols (TPP)-to modulate the fecal microbiota composition of healthy adults in an

Indexed as

AdultAgedAnthocyaninsAntioxidantsBlueberry PlantsColonFecesFemaleFermentationFlavonolsGastrointestinal MicrobiomeGlycosidesHealthy VolunteersHumansModels, AnatomicOxidative StressAnthocyaninsAntioxidantsFlavonolsGlycosidesPolyphenolsblueberriesgut microbiotahuman studyin vitrooxidative stresspolyphenols

Identifiers

PMID32932733
PMCPMC7551244

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.