Evidence map›Paper›PMID 32932759›Full record

ReviewBiomedicines2020

Algae Polyphenolic Compounds and Modern Antibacterial Strategies: Current Achievements and Immediate Prospects.

Natalya N Besednova, Boris G Andryukov, Tatyana S Zaporozhets, Sergey P Kryzhanovsky, Tatyana A Kuznetsova, Ludmila N Fedyanina, Ilona D Makarenkova, Tatyana N Zvyagintseva

Abstract readReview
In one paragraph

Review in Biomedicines, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Phlorotannin-Alginate Extract fromFoods (Basel, Switzerland) · 2025
    Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. Review
  13. Review
  14. Review
  15. Review
  16. Article
  17. Fermentation of micro- and macroalgae as a way to produce value-added products.Biotechnology reports (Amsterdam, Netherlands) · 2024
    Review
  18. From Ocean to Medicine: Harnessing Seaweed's Potential for Drug Development.International journal of molecular sciences · 2024
    Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Natalya N BesednovaSomov Research Institute of Epidemiology and Microbiology, 690087 Vladivostok, Russia.
Boris G AndryukovSomov Research Institute of Epidemiology and Microbiology, 690087 Vladivostok, Russia.ORCID 0000-0003-4456-808X
Tatyana S ZaporozhetsSomov Research Institute of Epidemiology and Microbiology, 690087 Vladivostok, Russia.
Sergey P KryzhanovskyMedical Association of the Far Eastern Branch of the Russian Academy of Sciences, 690022 Vladivostok, Russia.
Tatyana A KuznetsovaSomov Research Institute of Epidemiology and Microbiology, 690087 Vladivostok, Russia.
Ludmila N FedyaninaSchool of Biomedicine, Far Eastern Federal University (FEFU), 690091 Vladivostok, Russia.
Ilona D MakarenkovaSomov Research Institute of Epidemiology and Microbiology, 690087 Vladivostok, Russia.ORCID 0000-0001-6450-840X
Tatyana N ZvyagintsevaElyakov Pacific Institute of Bioorganic Chemistry, Far Eastern Branch of the Russian Academy of Sciences, 690022 Vladivostok, Russia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The increasing drug resistance of pathogenic microorganisms raises concern worldwide and necessitates the search for new natural compounds with antibacterial properties. Marine algae are considered a natural and attractive biotechnological source of novel antibiotics. The high antimicrobial activity of their polyphenolic compounds is a promising basis for designing innovative pharmaceuticals. They can become both a serious alternative to traditional antimicrobial agents and an effective supplement to antibiotic therapy. The present review summarizes the results of numerous studies on polyphenols from algae and the range of biological activities that determine their biomedical significance. The main focus is put on a group of the polyphenolic metabolites referred to as phlorotannins and, particularly, on their structural diversity and mechanisms of antimicrobial effects. Brown algae are an almost inexhaustible resource with a high biotechnological potential for obtaining these polyfunctional compounds. An opinion is expressed that the effectiveness of the antibacterial activity of phlorotannins depends on the methods of their extraction aimed at preserving the phenolic structure. The use of modern analytical tools opens up a broad range of opportunities for studying the metabolic pathways of phlorotannins and identifying their structural and functional relationships. The high antimicrobial activity of phlorotannins against both Gram-positive and Gram-negative bacteria provides a promising framework for creating novel drugs to be used in the treatment and prevention of infectious diseases.

Indexed as

antibacterial propertiesantibiofilm propertiesdrug resistance of microorganismsmarine algaephlorotannins (PT)polyphenols (PP)

Identifiers

PMID32932759
PMCPMC7554682

What Socratic holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.