Evidence map›Paper›PMID 32936401›Full record

ReviewClinical pharmacokinetics2021

Population Pharmacokinetics of Clotting Factor Concentrates and Desmopressin in Hemophilia.

Tim Preijers, Lisette M Schütte, Marieke J H A Kruip, Marjon H Cnossen, Frank W G Leebeek, Reinier M van Hest, Ron A A Mathôt

Open access · hybridAbstract readReview
In one paragraph

Review in Clinical pharmacokinetics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Tim PreijersHospital Pharmacy-Clinical Pharmacology, Academic University Medical Centers, Location AMC, Amsterdam, The Netherlands.ORCID 0000-0001-6953-0358
Lisette M SchütteDepartment of Hematology, Erasmus University Medical Center, Rotterdam, The Netherlands.ORCID 0000-0003-2101-4682
Marieke J H A KruipDepartment of Hematology, Erasmus University Medical Center, Rotterdam, The Netherlands.
Marjon H CnossenDepartment of Pediatric Hematology, Sophia Children's Hospital, Erasmus University Medical Center, Rotterdam, The Netherlands.
Frank W G LeebeekDepartment of Hematology, Erasmus University Medical Center, Rotterdam, The Netherlands.
Reinier M van HestHospital Pharmacy-Clinical Pharmacology, Academic University Medical Centers, Location AMC, Amsterdam, The Netherlands.
Ron A A MathôtHospital Pharmacy-Clinical Pharmacology, Academic University Medical Centers, Location AMC, Amsterdam, The Netherlands. r.mathot@amsterdamumc.nl.
Erasmus MC · NLAmsterdam UMC Location University of Amsterdam · NLAmsterdam University Medical Centers · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hemophilia A and B are bleeding disorders caused by a deficiency of clotting factor VIII and IX, respectively. Patients with severe hemophilia (< 0.01 IU mL

Indexed as

Blood Coagulation FactorsDeamino Arginine VasopressinHemophilia AChildHumansBlood Coagulation FactorsDeamino Arginine Vasopressin

Identifiers

PMID32936401
PMCPMC7808974
OpenAlexW3084936083

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.