Evidence map›Paper›PMID 32942674›Full record

ReviewBiomolecules2020

Traditional Herbal Medicine Mediated Regulations during Head and Neck Carcinogenesis.

Xiang-Yun Lan, Tzu-Ting Chung, Chien-Ling Huang, Yi-Jang Lee, Wan-Chun Li

Open access · goldAbstract readReview
In one paragraph

Review in Biomolecules, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Xiang-Yun LanInstitute of Oral Biology, School of Dentistry, National Yang-Ming University, Taipei 11221, Taiwan.
Tzu-Ting ChungDepartment of Dentistry, School of Dentistry, National Yang-Ming University, Taipei 11221, Taiwan.
Chien-Ling HuangDepartment of Health Technology and Informatics (HTI), The Hong Kong Polytechnic University (PolyU), Hung Hom, Kowloon, Hong Kong, SAR, China.
Yi-Jang LeeDepartment of Biomedical Imaging and Radiological Sciences, National Yang-Ming University, Taipei 11221, Taiwan.ORCID 0000-0002-0340-7557
Wan-Chun LiInstitute of Oral Biology, School of Dentistry, National Yang-Ming University, Taipei 11221, Taiwan.ORCID 0000-0003-0481-4215
National Yang Ming Chiao Tung University · TWHong Kong Polytechnic University · HK

Funding

Ministry of Science and Technology, Taiwan 106-2314-B-010-005-MY3Ministry of Science and Technology, Taiwan 109-2628-B-010-008-
6 · The paper itself

Abstract

Head and neck squamous cell carcinoma (HNSCC) is one of the most prevalent neoplasms worldwide. It is well recognized that environmental challenges such as smoking, viral infection and alcohol consumption are key factors underlying HNSCC pathogenesis. Other than major clinical interventions (e.g., surgical resection, chemical and radiotherapy) that have been routinely practiced over years, adjuvant anticancer agents from Traditional Herbal Medicine (THM) are proposed, either alone or together with conventional therapies, to be experimentally effective for improving treatment efficacy in different cancers including HNSCCs. At a cellular and molecular basis, THM extracts could modulate different malignant indices via distinct signaling pathways and provide better control in HNSCC malignancy and its clinical complications such as radiotherapy-induced xerostomia/oral mucositis. In this article, we aim to systemically review the impacts of THM in regulating HNSCC tumorous identities and its potential perspective for clinical use.

Indexed as

Antineoplastic Agents, PhytogenicApoptosisCarcinoma, Squamous CellCell MovementCell ProliferationGamma RaysGene Expression Regulation, NeoplasticHead and Neck NeoplasmsHumansLymphatic MetastasisMedicine, Chinese TraditionalNeoplasm ProteinsNeovascularization, PathologicPlants, MedicinalStomatitisTaiwanAntineoplastic Agents, PhytogenicNeoplasm Proteinsangiogenesishead and neck cancerintegrative therapymetastasisoral mucositistraditional herbal medicinetumor growthxerostomia

Identifiers

PMID32942674
PMCPMC7565208
OpenAlexW3085348705

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.