Evidence map›Paper›PMID 32953199›Full record

ArticleJournal of bio-X research2019

Integrative omics analysis identifies macrophage migration inhibitory factor signaling pathways underlying human hepatic fibrogenesis and fibrosis.

Zhipeng Liu, Naga Chalasani, Jingmei Lin, Samer Gawrieh, Yuan He, Yan J Tseng, Wanqing Liu

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of bio-X research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. The Genetic Architecture of Carbon Tetrachloride-Induced Liver Fibrosis in Mice.Cellular and molecular gastroenterology and hepatology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Zhipeng LiuDepartment of Medicinal Chemistry and Molecular Pharmacology, College of Pharmacy, Purdue University, West Lafayette.
Naga ChalasaniDivision of Gastroenterology and Hepatology, Indianapolis, IN.
Jingmei LinDepartment of Pathology, Indiana University School of Medicine, Indianapolis, IN.
Samer GawriehDivision of Gastroenterology and Hepatology, Indianapolis, IN.
Yuan HeDepartment of Biochemistry, Microbiology and Immunology, School of Medicine, Wayne State University, Detroit, MI, USA.
Yan J TsengDepartment of Biochemistry, Microbiology and Immunology, School of Medicine, Wayne State University, Detroit, MI, USA.
Wanqing LiuDepartment of Pharmaceutical Sciences, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, MI, USA.
Indiana University – Purdue University Indianapolis · USPurdue University West Lafayette · USThe Barbara Ann Karmanos Cancer Institute · US

Funding

Fatty Acid Desaturase 1 (FADS1) Variants and Non-alcoholic Fatty Liver DiseaseR01DK106540 · NIDDK · WAYNE STATE UNIVERSITY · PI LIU, WANQING · 2016 to 2020
$1.9M
NIDDK NIH HHS R01 DK106540
6 · The paper itself

Abstract

The genetic basis underlying liver fibrosis remains largely unknown. We conducted a study to identify genetic alleles and underlying pathways associated with hepatic fibrogenesis and fibrosis at the genome-wide level in 121 human livers. By accepting a liberal significance level of

Indexed as

alpha-smooth muscle actingenetic susceptibilitygenomicshepatic fibrosismacrophage migration inhibitory factorpathway enrichment analysis

Identifiers

PMID32953199
PMCPMC7500331
OpenAlexW2940131840

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.