Evidence mapPaperPMID 32955366Full record

ArticleJournal of the American Heart Association2020

Carotid-Femoral Pulse Wave Velocity as a Risk Marker for Development of Complications in Type 1 Diabetes Mellitus.

Ninna Hahn Tougaard, Simone Theilade, Signe Abitz Winther, Nete Tofte, Tarunveer Singh Ahluwalia, Tine Willum Hansen, Peter Rossing, Marie Frimodt-Møller

Registry-linked trialAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05478707 (Therapeutic Strategies for Microvascular Dysfunction in Type 1 Diabetes), which is not on this map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05478707 phase2recruitingstarted 2023, after this paper: background citation

Therapeutic Strategies for Microvascular Dysfunction in Type 1 Diabetes

Ran2023Enrolled47Registered outcomes5Posted comparisons0ConditionsDiabetes Mellitus, Type 1, Endothelial DysfunctionArmsDulaglutide, Placebo
Open the trial in the graph
3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Ultrasound strain mapping of the non-aneurysmal abdominal aorta for detecting age-related aortic stiffening.International journal of cardiology. Cardiovascular risk and prevention · 2026
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  16. Higher HbACardiovascular diabetology · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ninna Hahn TougaardSteno Diabetes Center Copenhagen Gentofte Denmark.
Simone TheiladeSteno Diabetes Center Copenhagen Gentofte Denmark.
Signe Abitz WintherSteno Diabetes Center Copenhagen Gentofte Denmark.
Nete TofteSteno Diabetes Center Copenhagen Gentofte Denmark.
Tarunveer Singh AhluwaliaSteno Diabetes Center Copenhagen Gentofte Denmark.
Tine Willum HansenSteno Diabetes Center Copenhagen Gentofte Denmark.
Peter RossingSteno Diabetes Center Copenhagen Gentofte Denmark.
Marie Frimodt-MøllerSteno Diabetes Center Copenhagen Gentofte Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background The value of carotid-femoral pulse wave velocity (cfPWV) as risk factor for development of complications in type 1 diabetes mellitus remains to be determined. We investigated associations between cfPWV and renal outcomes, cardiovascular events, and all-cause mortality in people with type 1 diabetes mellitus. Methods and Results cfPWV was measured with SphygmoCor in 633 people with type 1 diabetes mellitus. Median (interquartile range) follow-up was 6.2 (5.8-6.7) years. End points included progression in albuminuria group, decline in estimated glomerular filtration rate (eGFR) ≥30%, end-stage kidney disease, cardiovascular event, mortality, and a composite renal end point. Hazard ratios (HRs) were calculated per 1-SD increase in cfPWV. Adjustments included age, sex, hemoglobin A1c, mean arterial pressure, body mass index, low-density lipoprotein cholesterol, smoking, urine albumin excretion rate, and eGFR. The cohort included 45% women, mean (SD) age was 54 (13) years, mean (SD) eGFR was 83.2 (27.9) mL/min per 1.73 m

Indexed as

Carotid-Femoral Pulse Wave VelocityAdultAlbuminuriaBiomarkersDiabetes Mellitus, Type 1Diabetic CardiomyopathiesDiabetic NephropathiesFemaleGlomerular Filtration RateHumansMaleMiddle AgedProspective StudiesRisk FactorsVascular StiffnessBiomarkersarterial stiffnesscarotid-femoral pulse wave velocitydiabetic complicationstype 1 diabetes mellitus

Identifiers

PMID32955366
PMCPMC7792427

What Socratic holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.