Evidence map›Paper›PMID 32961769›Full record

ReviewLife (Basel, Switzerland)2020

Current Progress and Perspective: Clinical Imaging of Islet Transplantation.

Taylor Marie Richards, Aixia Sun, Hasaan Hayat, Neil Robertson, Zhaoda Zhang, Jinda Fan, Ping Wang

Abstract readReview
In one paragraph

Review in Life (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Frontiers in endocrinology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Taylor Marie RichardsPrecision Health Program, Michigan State University, East Lansing, MI 48823, USA.
Aixia SunPrecision Health Program, Michigan State University, East Lansing, MI 48823, USA.
Hasaan HayatPrecision Health Program, Michigan State University, East Lansing, MI 48823, USA.ORCID 0000-0001-9294-1016
Neil RobertsonPrecision Health Program, Michigan State University, East Lansing, MI 48823, USA.
Zhaoda ZhangAthinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Charlestown, MA 02129, USA.
Jinda FanDepartment of Radiology, College of Human Medicine, Michigan State University, East Lansing, MI 48824, USA.ORCID 0000-0003-3098-3397
Ping WangPrecision Health Program, Michigan State University, East Lansing, MI 48823, USA.ORCID 0000-0001-6712-8939

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Islet transplantation has great potential as a cure for type 1 diabetes. At present; the lack of a clinically validated non-invasive imaging method to track islet grafts limits the success of this treatment. Some major clinical imaging modalities and various molecular probes, which have been studied for non-invasive monitoring of transplanted islets, could potentially fulfill the goal of understanding pathophysiology of the functional status and viability of the islet grafts. In this current review, we summarize the recent clinical studies of a variety of imaging modalities and molecular probes for non-invasive imaging of transplanted beta cell mass. This review also includes discussions on in vivo detection of endogenous beta cell mass using clinical imaging modalities and various molecular probes, which will be useful for longitudinally detecting the status of islet transplantation in Type 1 diabetic patients. For the conclusion and perspectives, we highlight the applications of multimodality and novel imaging methods in islet transplantation.

Indexed as

beta cell mass (BCM)islet transplantationmagnetic resonance Imaging (MRI)positron emission tomography (PET)single photon emission computed tomography (SPECT)type 1 diabetes (T1D)

Identifiers

PMID32961769
PMCPMC7555367

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.