Evidence map›Paper›PMID 32963042›Full record

ArticleBMJ case reports2020

Adrenal medullary hyperplasia mimicking pheochromocytoma.

Annalisa Montebello, Michelle Ann Ceci, Sandro Vella

Abstract readCase Reports
In one paragraph

Article in BMJ case reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Adrenal Medullary Hyperplasia: A Systematic Review and Meta-analysis.The Journal of clinical endocrinology and metabolism · 2023
    Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Annalisa MontebelloDiabetes and Endocrinology Department, Mater Dei Hospital, Msida, Malta a.montebello@smd18.qmul.ac.uk.ORCID http://orcid.org/0000-0002-8676-4233
Michelle Ann CeciPathology Department, Mater Dei Hospital, Msida, Malta.
Sandro VellaDiabetes and Endocrinology Department, Mater Dei Hospital, Msida, Malta.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 59-year-old woman, a known case of hypertension, was incidentally diagnosed with a large right-sided adrenal mass. Investigations for a functional adrenal lesion resulted in very high preoperative norepinephrine levels. A right adrenalectomy was performed. Histology showed adrenal medullary hyperplasia (AMH). AMH is a rare diagnosis and its incidence is poorly documented in the literature. This is a benign entity which resembles pheochromocytoma (PCC) in both clinical and biochemical manner. AMH is usually bilateral and may occur in isolation or in association with PCC. In fact, some authors consider it to be a precursor to PCC. Thus, these patients need long-term follow-up in view of the risk of development of PCC later.

Indexed as

AdrenalectomyAdrenal Gland NeoplasmsAdrenal MedullaCatecholaminesDiagnosis, DifferentialFemaleHumansHyperplasiaHypertensionIncidental FindingsMagnetic Resonance ImagingMetanephrineMiddle AgedNorepinephrinePheochromocytomaPositron Emission Tomography Computed TomographyCatecholaminesMetanephrineNorepinephrineRadiopharmaceuticalsadrenal disordersgeneral surgeryradiology

Identifiers

PMID32963042
PMCPMC7509954

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.