Evidence map›Paper›PMID 32963695›Full record

ArticleOxidative medicine and cellular longevity2020

PARK7 Diminishes Oxidative Stress-Induced Mucosal Damage in Celiac Disease.

Apor Veres-Székely, Mária Bernáth, Domonkos Pap, Réka Rokonay, Beáta Szebeni, István M Takács, Rita Lippai, Áron Cseh, Attila J Szabó, Ádám Vannay

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Comparison of MicroalgaeMarine drugs · 2024
    Article
  4. Review
  5. Article
  6. Role of Mitophagy in Regulating Intestinal Oxidative Damage.Antioxidants (Basel, Switzerland) · 2023
    Review
  7. PARK7/DJ-1 as a Therapeutic Target in Gut-Brain Axis Diseases.International journal of molecular sciences · 2022
    Review
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Apor Veres-Székely1st Department of Paediatrics, Semmelweis University, 1085 Budapest, Hungary.
Mária Bernáth1st Department of Paediatrics, Semmelweis University, 1085 Budapest, Hungary.
Domonkos PapMTA-SE Pediatrics and Nephrology Research Group, 1085 Budapest, Hungary.
Réka Rokonay1st Department of Paediatrics, Semmelweis University, 1085 Budapest, Hungary.
Beáta SzebeniMTA-SE Pediatrics and Nephrology Research Group, 1085 Budapest, Hungary.ORCID https://orcid.org/0000-0001-7577-9803
István M Takács1st Department of Paediatrics, Semmelweis University, 1085 Budapest, Hungary.
Rita Lippai1st Department of Paediatrics, Semmelweis University, 1085 Budapest, Hungary.
Áron Cseh1st Department of Paediatrics, Semmelweis University, 1085 Budapest, Hungary.
Attila J Szabó1st Department of Paediatrics, Semmelweis University, 1085 Budapest, Hungary.
Ádám Vannay1st Department of Paediatrics, Semmelweis University, 1085 Budapest, Hungary.ORCID https://orcid.org/0000-0001-7412-4733
Semmelweis University · HU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coeliac disease (CD) is a chronic, immune-mediated small intestinal enteropathy, accompanied with gluten-triggered oxidative damage of duodenal mucosa. Previously, our research group reported an increased mucosal level of the antioxidant protein Parkinson's disease 7 (PARK7) in children with CD. In the present study, we investigated the role of increased PARK7 level on the epithelial cell and mucosal integrity of the small intestine. The presence of PARK7 was investigated using immunofluorescent staining on duodenal mucosa of children with CD and on FHs74Int duodenal epithelial cells. To investigate the role of oxidative stress, FHs74Int cells were treated with H

Indexed as

Oxidative StressBenzamidesCeliac DiseaseCell AdhesionCell DeathCell LineCytoskeletonDuodenumEpithelial CellsHumansIntestinal MucosaIntracellular SpaceModels, BiologicalPermeabilityProtein Deglycase DJ-1PyridinesBenzamidesN-(4-(8-methyl(4-hydroimidazo(1,2-a)pyridin-2-yl))phenyl)(3,4,5-trimethoxyphenyl)carboxamidePARK7 protein, humanProtein Deglycase DJ-1PyridinesReactive Oxygen Species

Identifiers

PMID32963695
PMCPMC7492931
OpenAlexW3083673288

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.